Boulanger Denis, Doucouré Souleymane, Grout L., Ngom A., Rogerie F., Cornélie Sylvie, Sokhna Cheikh, Mouchet François, Riveau G., Simondon François, Remoué Franck. (2011). Immunoglobulin G antibody profiles against Anopheles salivary proteins in domestic animals in Senegal. Journal of Medical Entomology, 48 (3), p. 691-693. ISSN 0022-2585.
Titre du document
Immunoglobulin G antibody profiles against Anopheles salivary proteins in domestic animals in Senegal
Année de publication
2011
Auteurs
Boulanger Denis, Doucouré Souleymane, Grout L., Ngom A., Rogerie F., Cornélie Sylvie, Sokhna Cheikh, Mouchet François, Riveau G., Simondon François, Remoué Franck
Source
Journal of Medical Entomology, 2011,
48 (3), p. 691-693 ISSN 0022-2585
Although domestic animals may not be permissive for Plasmodium, they could nevertheless play a role in the epidemiology of malaria by attracting Anopheles away from humans. To investigate interactions between domestic animals and mosquitoes, we assayed immunoglobulin G (IgG) antibodies directed against the salivary proteins of Anopheles gambiae in domestic animals living in Senegalese villages where malaria is endemic. By Western blotting, sera from bovines (n = 6), ovines (n = 36), and caprines (n = 36) did not react with Anopheles whole saliva. In contrast, equine sera recognized proteins in both saliva and salivary gland extracts. Two of the major immunogens (32 and 72 kDa) were also reactive in extracts from other major mosquito genera (Aedes and Culex), but reactions to Anopheles-specific antigens were detected in 12 of 17 horses. These data suggest that horses strongly react to Anopheles bites, and further experiments on horses are warranted to investigate the impact of this domestic animal species on the transmission of human malaria.
Plan de classement
Entomologie médicale / Parasitologie / Virologie [052]
;
Sciences du monde animal [080]
Localisation
Fonds IRD [F B010053788]
Identifiant IRD
fdi:010053788
