@article{fdi:010053787,
  title = {{C}ombining piperonyl butoxide and dinotefuran restores the efficacy of deltamethrin mosquito nets against resistant {A}nopheles gambiae ({D}iptera : {C}ulicidae)},
  author = {{D}arriet, {F}r{\'e}d{\'e}ric and {C}handre, {F}abrice},
  editor = {},
  language = {{ENG}},
  abstract = {{O}ne strategy suggested for the management of mosquito insecticide resistance consists of combining a pyrethroid with an insecticide that has a different mode of action. {T}o restore the efficacy of deltamethrin (pyrethroid) against pyrethroid-resistant strain of {A}nopheles gambiae {G}iles ({VKPR}: homozygous {K}dr), deltamethrin was combined with the neonicotinoid insecticide dinotefuran and piperonyl butoxide ({PBO}). {B}ednets impregnated with deltamethrin, dinotefuran, and {PBO} alone and in combination were tested in the laboratory. {K}nockdown ({KD}) and mortality were measured using {WHO} cone tests on susceptible and pyrethroid-resistant adult mosquitoes. {T}he combination of deltamethrin and {PBO} was synergistic against resistant female {A}n. gambiae (58.2% mortality). {B}oth mortality and knockdown time ({KD}t(50/95) values) of the tricomponent mixture on the {VKPR} strain were similar to the insecticidal activity of deltamethrin on the pyrethroid-susceptible {KIS} strain (98.8 and 100% mortality, respectively). {T}he three-compound mixture of deltamethrin + {PBO} + dinotefuran showed an insecticidal efficacy greater than the deltamethrin + {PBO} mixture to the extent of completely restoring the efficacy of deltamethrin on pyrethroid-resistant {A}n. gambiae.},
  keywords = {deltamethrin ; dinotefuran ; piperonyl butoxide ; resistance management ; synergy},
  booktitle = {},
  journal = {{J}ournal of {M}edical {E}ntomology},
  volume = {48},
  numero = {4},
  pages = {952--955},
  ISSN = {0022-2585},
  year = {2011},
  DOI = {10.1603/me11022},
  URL = {https://www.documentation.ird.fr/hor/fdi:010053787},
}