Thomas F. auteur aut IRD Elguero Eric auteur aut IRD Brodeur J. auteur aut IRD Le Goff J. auteur aut IRD Missé Dorothée auteur aut IRD text journalArticle eng text/pdf born digital access Herpes simplex virus type-2 (HSV-2) has been identified as a possible aetiological agent of cancer in humans, especially prostate cancer, but results remain controversial. Here, we have addressed this question using a medical geography approach based on the national incidence of various cancers and seroprevalence of HSV-2 in 64 countries worldwide. We corrected reports of cancer incidence for national gross domestic product (GDP) because living in a wealthy nation likely increases the probability of having a cancer detected. Data were also corrected for latitude and diet. Our analysis not only confirms that prostate cancer and HSV-2 seroprevalence are positively associated, but it also reveals the existence of a positive relationship between HSV-2 and melanoma incidence in both men and women. These results, though correlational, suggest that HSV-2 should continue to be investigated as a possible oncogenic pathogen of humans. specialized Genital herpes Medical geography Prostate cancer Melanoma 052 11 6 1239-1242 2011 1567-1348 https://www.documentation.ird.fr/hor/fdi:010053762 10.1016/j.meegid.2011.04.009 1567-1348 [F B010053762] https://www.documentation.ird.fr/hor/fdi:010053762 https://www.documentation.ird.fr/intranet/publi/2011/09/010053762.pdf Accès réservé (Intranet de l'IRD) IRD - Base Horizon / Pleins textes 2011-10-06 2023-04-18 fdi:010053762 fre