Patramool Sirilaksana auteur aut IRD Surasombatpattana Pornapat auteur aut IRD Luplertlop N. auteur aut IRD Seveno M. auteur aut IRD Choumet V. auteur aut IRD Thomas F. auteur aut IRD Missé Dorothée auteur aut IRD text journalArticle eng text/pdf reformatted digital access Background: Proteomic analysis was performed to identify proteins regulated during infection by Dengue serotypes 1 and 3 in an Aedes albopictus cell line. The potential of these viruses to cause severe disease at primary infection is of interest although few studies have been performed with these two Dengue serotypes. Results: The most relevant observation of our study is the significant overexpression of proteins involved in the cellular stress response and the glycolysis pathway after 48 hours of infection. Viral infection activates the translation of some host genes, which may result in stress due to responses involving unfolded proteins. Conclusions: Therefore, the oxidation reduction and glycolytic mechanisms could participate in the antiviral response against Dengue virus. The results of our study should help to improve our knowledge of the virus-mosquito interaction at a cellular level with the aim of designing efficient strategies for the control of Dengue virus. specialized 052 4 138 2011 1756-3305 https://www.documentation.ird.fr/hor/fdi:010053755 10.1186/1756-3305-4-138 1756-3305 [F B010053755] https://www.documentation.ird.fr/hor/fdi:010053755 https://horizon.documentation.ird.fr/exl-doc/pleins_textes/divers17-09/010053755.pdf IRD - Base Horizon / Pleins textes 2011-09-01 2024-04-29 fdi:010053755 fre