@article{fdi:010053755, title = {{P}roteomic analysis of an {A}edes albopictus cell line infected with {D}engue serotypes 1 and 3 viruses}, author = {{P}atramool, {S}irilaksana and {S}urasombatpattana, {P}ornapat and {L}uplertlop, {N}. and {S}eveno, {M}. and {C}houmet, {V}. and {T}homas, {F}. and {M}iss{\'e}, {D}oroth{\'e}e}, editor = {}, language = {{ENG}}, abstract = {{B}ackground: {P}roteomic analysis was performed to identify proteins regulated during infection by {D}engue serotypes 1 and 3 in an {A}edes albopictus cell line. {T}he potential of these viruses to cause severe disease at primary infection is of interest although few studies have been performed with these two {D}engue serotypes. {R}esults: {T}he most relevant observation of our study is the significant overexpression of proteins involved in the cellular stress response and the glycolysis pathway after 48 hours of infection. {V}iral infection activates the translation of some host genes, which may result in stress due to responses involving unfolded proteins. {C}onclusions: {T}herefore, the oxidation reduction and glycolytic mechanisms could participate in the antiviral response against {D}engue virus. {T}he results of our study should help to improve our knowledge of the virus-mosquito interaction at a cellular level with the aim of designing efficient strategies for the control of {D}engue virus.}, keywords = {}, booktitle = {}, journal = {{P}arasites and {V}ectors}, volume = {4}, numero = {}, pages = {138}, ISSN = {1756-3305}, year = {2011}, DOI = {10.1186/1756-3305-4-138}, URL = {https://www.documentation.ird.fr/hor/fdi:010053755}, }