%0 Journal Article
%9 ACL : Articles dans des revues avec comité de lecture répertoriées par l'AERES
%A Nga, T. T.
%A Winichagoon, P.
%A Dijkhuizen, M. A.
%A Khan, N. C.
%A Wasantwisut, E.
%A Wieringa, Franck
%T Decreased parasite load and improved cognitive outcomes caused by deworming and consumption of multi-micronutrient fortified biscuits in rural Vietnamese schoolchildren
%D 2011
%L fdi:010053738
%G ENG
%J American Journal of Tropical Medicine and Hygiene
%@ 0002-9637
%M ISI:000293613000025
%N 2
%P 333-340
%R 10.4269/ajtmh.2011.10-0651
%U https://www.documentation.ird.fr/hor/fdi:010053738
%> https://horizon.documentation.ird.fr/exl-doc/pleins_textes/divers20-08/010053738.pdf
%V 85
%W Horizon (IRD)
%X Micronutrient deficiencies are associated with impaired growth and cognitive function. A school-based fortification program might benefit schoolchildren but a high prevalence of parasite infestation might affect effectiveness. A randomized, double-blind, placebo-controlled 2 x 2 factorial trial was conducted to assess the efficacy of multi-micronutrient fortified biscuits with or without de-worming on growth, cognitive function, and parasite load in Vietnamese schoolchildren. Schoolchildren (n = 510), 6-8 years of age were randomly allocated to receive albendazole or placebo at baseline and four months of multi-micronutrient fortified biscuits (FB) or non-fortified biscuits. Children receiving FB for four months scored higher on two cognitive tests: Raven's Colored Progressive Matrices and the Digit Span Forward test. Children receiving albendazole plus FB had the lowest parasite load after four months. In children receiving FB, mid-upper arm circumference was slightly improved (+0.082 cm) but there were no differences in other indexes of anthropometry. Combining multi-micronutrient fortified biscuits with de-worming is an effective strategy.
%$ 054