@article{fdi:010053657,
  title = {{P}yrethroid resistance reduces the efficacy of space sprays for dengue control on the {I}sland of {M}artinique ({C}aribbean)},
  author = {{M}arcombe, {S}{\'e}bastien and {D}arriet, {F}r{\'e}d{\'e}ric and {T}olosa, {M}. and {A}gnew, {P}hilip and {D}uchon, {S}t{\'e}phane and {E}tienne, {M}. and {T}cha, {M}. {M}. {Y}. and {C}handre, {F}abrice and {C}orbel, {V}incent and {Y}ebakima, {A}ndr{\'e}},
  editor = {},
  language = {{ENG}},
  abstract = {{B}ackground: {D}engue fever is reemerging on the island of {M}artinique and is a serious threat for the human population. {D}uring dengue epidemics, adult {A}edes aegypti control with pyrethroid space sprays is implemented in order to rapidly reduce transmission. {U}nfortunately, vector control programs are facing operational challenges with the emergence of pyrethroid resistant {A}e. aegypti populations. {M}ethodology/{P}rincipal {F}indings: {T}o assess the impact of pyrethroid resistance on the efficacy of treatments, applications of deltamethrin and natural pyrethrins were performed with vehicle-mounted thermal foggers in 9 localities of {M}artinique, where {A}e. aegypti populations are strongly resistant to pyrethroids. {E}fficacy was assessed by monitoring mortality rates of naturally resistant and laboratory susceptible mosquitoes placed in sentinel cages. {B}efore, during and after spraying, larval and adult densities were estimated. {R}esults showed high mortality rates of susceptible sentinel mosquitoes treated with deltamethrin while resistant mosquitoes exhibited very low mortality. {T}here was no reduction of either larval or adult {A}e. aegypti population densities after treatments. {C}onclusions/{S}ignificance: {T}his is the first documented evidence that pyrethroid resistance impedes dengue vector control using pyrethroid-based treatments. {T}hese results emphasize the need for alternative tools and strategies for dengue control programs.},
  keywords = {{MARTINIQUE}},
  booktitle = {},
  journal = {{P}los {N}eglected {T}ropical {D}iseases},
  volume = {5},
  numero = {6},
  pages = {e1202},
  ISSN = {1935-2727},
  year = {2011},
  DOI = {10.1371/journal.pntd.0001202},
  URL = {https://www.documentation.ird.fr/hor/fdi:010053657},
}