@article{fdi:010053637, title = {{I}nsecticide susceptibility of {A}edes aegypti and {A}edes albopictus in {C}entral {A}frica}, author = {{K}amgang, {B}asile and {M}arcombe, {S}{\'e}bastien and {C}handre, {F}abrice and {N}choutpouen, {E}. and {N}wane, {P}. and {E}tang, {J}. and {C}orbel, {V}incent and {P}aupy, {C}hristophe}, editor = {}, language = {{ENG}}, abstract = {{B}ackground: {A}edes aegypti ({L}innaeus, 1762) and {A}edes albopictus ({S}kuse, 1894) are the main vectors of dengue ({DENV}) and chikungunya ({CHIKV}) viruses worldwide. {A}s there is still no vaccine or specific treatment for {DENV} and {CHIKV}, vector control remains the cornerstone of prevention and outbreak control. {U}nfortunately, vector control programs are facing operational challenges with mosquitoes becoming resistant to commonly used insecticides in several areas through the world. {T}hroughout {C}entral {A}frica no recent data are available susceptible/resistant status of either vector species since the introduction/arrival of {A}e. albopictus in this area. {W}e therefore studied the level of resistance of these two major vectors to insecticides commonly used in {A}frica for mosquito control. {R}esults: {A}edes aegypti and {A}e. albopictus were sampled in six urban localities of {C}ameroon ({G}aroua, {B}ertoua, {Y}aounde, {B}afia, {B}uea) and {G}abon ({L}ibreville). {L}arval bioassays, carried out to determine the lethal concentrations ({LC}50 and {LC}95) and resistance ratios ({RR}50 and {RR}95) suggested that both vector species were susceptible to {B}ti ({B}acillus thuringiensis var israeliensis) and temephos. {B}ioassays were also performed on adults using {WHO} diagnostic test kits to assess phenotypic resistance to deltamethrin, {DDT}, fenitrothion and propoxur. {T}hese experiments showed that one population of {A}e. aegypti ({L}ibreville) and two populations of {A}e. albopictus ({B}uea and {Y}aounde) were resistant to {DDT} (mortality 36% to 71%). {R}esistance to deltamethrin was also suspected in {A}e. albopictus from {Y}aounde (83% mortality). {A}ll other field mosquito populations were susceptible to deltamethrin, {DDT}, fenitrothion and propoxur. {N}o increase in the knockdown times ({K}dt(50) and {K}dt(95)) was noted in the {Y}aounde resistant population compared to other {A}e. albopictus populations, suggesting the possible involvement of metabolic resistance to deltamethrin and {DDT}. {C}onclusion: {I}n view of the recent increase in dengue and chikungunya outbreaks in {C}entral {A}frica, these unique comparative data on the insecticide susceptibility of {A}e. aegypti and {A}e. albopictus could help public health services to design more effective vector control measures.}, keywords = {{CAMEROUN}}, booktitle = {}, journal = {{P}arasites and {V}ectors}, volume = {4}, numero = {}, pages = {79 [9 ]}, ISSN = {1756-3305}, year = {2011}, DOI = {10.1186/1756-3305-4-79}, URL = {https://www.documentation.ird.fr/hor/fdi:010053637}, }