@article{fdi:010053629,
  title = {{N}eutralization of {V}ipera and {M}acrovipera venoms by two experimental polyvalent antisera : a study of paraspecificity},
  author = {{A}rchundia, {I}. {G}. and de {R}oodt, {A}. {R}. and {R}amos-{C}errillo, {B}. and {C}hippaux, {J}ean-{P}hilippe and {O}lguin-{P}erez, {L}. and {A}lagon, {A}. and {S}tock, {R}. {P}.},
  editor = {},
  language = {{ENG}},
  abstract = {{W}e conducted an extensive study of neutralization of lethality of 11 species and one subspecies of snakes of the genus {V}ipera, and of five species of {M}acrovipera, by two experimental equine antisera. {O}ne antiserum was a trivalent preparation raised against the venoms of {V}ipera aspis aspis, {V}ipera berus berus and {V}ipera ammodytes ammodytes; the other was a pentavalent preparation that also included venoms of {V}ipera (now {M}ontivipera) xanthina and {M}acrovipera lebetina obtusa. {W}e measured specific neutralization of lethality against all venoms included in the immunization schemes, and paraspecific neutralization against the venoms of {V}ipera ammodytes montandoni, {V}ipera ({M}ontivipera) bornmuelleri, {V}ipera latastei, {V}ipera ({M}o.) latifii, {V}ipera ({M}o.) lotievi, {V}ipera ({D}aboia) palaestinae, {V}ipera ({M}o.) raddei and {V}ipera seoanei, as well as against {M}acrovipera ({D}.) desert, {M}acrovipera lebetina cernovi, {M}acrovipera lebetina turanica and {M}acrovipera schweitzeri. {W}e found an important degree of paraspecific protection within each genera (omitting recent reclassification) that was quite independent of both the lethal potency of the venoms and their geographic origin. {T}his information may be of use to clinicians charged with the treatment of {V}ipera or {M}acrovipera envenomations with non-specific antivenoms.},
  keywords = {{V}ipera ; {M}acrovipera ; {D}aboia ; {M}ontivipera ; {A}ntivenom ; {P}araspecific ; neutralization},
  booktitle = {},
  journal = {{T}oxicon},
  volume = {57},
  numero = {7-8},
  pages = {1049--1056},
  ISSN = {0041-0101},
  year = {2011},
  DOI = {10.1016/j.toxicon.2011.04.009},
  URL = {https://www.documentation.ird.fr/hor/fdi:010053629},
}