@article{fdi:010053508,
  title = {{A}ryl-homoserine lactone quorum sensing in stem-nodulating photosynthetic bradyrhizobia},
  author = {{A}hlgren, {N}. {A}. and {H}arwood, {C}. {S}. and {S}chaefer, {A}. {L}. and {G}iraud, {E}ric and {G}reenberg, {E}. {P}.},
  editor = {},
  language = {{ENG}},
  abstract = {{M}any {P}roteobacteria possess {L}ux{I}-{L}ux{R}-type quorum-sensing systems that produce and detect fatty acyl-homoserine lactone ({HSL}) signals. {T}he photoheterotroph {R}hodopseudomonas palustris is unusual in that it produces and detects an aryl-{HSL}, p-coumaroyl-{HSL}, and signal production requires an exogenous source of p-coumarate. {A} photosynthetic stem-nodulating member of the genus {B}radyrhizobium produces a small molecule signal that elicits an {R}. palustris quorum-sensing response. {H}ere, we show that this signal is cinnamoyl-{HSL} and that cinnamoyl-{HSL} is produced by the {L}ux{I} homolog {B}ra{I} and detected by {B}ra{R}. {C}innamoyl-{HSL} reaches concentrations on the order of 50 n{M} in cultures of stem-nodulating bradyrhizobia grown in the presence or absence of cinnamate. {A}cyl-{HSL}s often reach concentrations of 0.1-30 mu {M} in bacterial cultures, and generally, {L}ux{R}-type receptors respond to signals in a concentration range from 5 to a few hundred nanomolar. {O}ur stem-nodulating {B}radyrhizobium strain responds to picomolar concentrations of cinnamoyl-{HSL} and thus, produces cinnamoyl-{HSL} in excess of the levels required for a signal response without an exogenous source of cinnamate. {T}he ability of {B}radyrhizobium to produce and respond to cinnamoyl-{HSL} shows that aryl-{HSL} production is not unique to {R}. palustris, that the aromatic acid substrate for aryl-{HSL} synthesis does not have to be supplied exogenously, and that some acyl-{HSL} quorum-sensing systems may function at very low signal production and response levels.},
  keywords = {bacterial communication ; {L}ux{I}-{L}ux{R} homologs ; sociomicrobiology},
  booktitle = {},
  journal = {{P}roceedings of the {N}ational {A}cademy of {S}ciences of the {U}nited {S}tates of {A}merica},
  volume = {108},
  numero = {17},
  pages = {7183--7188},
  ISSN = {0027-8424},
  year = {2011},
  DOI = {10.1073/pnas.1103821108},
  URL = {https://www.documentation.ird.fr/hor/fdi:010053508},
}