@article{fdi:010053448, title = {{E}stimate of the burden of snakebites in sub-{S}aharan {A}frica : a meta-analytic approach}, author = {{C}hippaux, {J}ean-{P}hilippe}, editor = {}, language = {{ENG}}, abstract = {{S}nakebites represent an important neglected public health problem in many developing countries. {T}here is a lack of epidemiological data, which would be very useful for the organisation of snakebite management and provision of antivenom. {A}n extensive literature search for the years 1970-2010 was performed. {D}ata were analysed using meta-analysis to take into account the heterogeneity between the studies and their respective weight. {I}ncidence, mortality and population at risk were estimated after stratification according to the environment (urban or rural) and survey methodologies (national, hospital or community studies). {T}he incidence of snakebite was inversely correlated with population density. {T}he number of envenomings was estimated at 314,078 [{C}195% = 251,513-377,462], of which 95% occurred in rural areas. {T}he remainder occurred in cities. {T}he annual mortality was estimated at 7,331 [5,148-9,568], of which 97% occurred in a rural environment. {T}he annual number of amputations ranged from 5,908 to 14,614. {T}he population most at risk was young men engaged in agricultural or pastoral labours. {H}ousehold surveys indicated that actual incidence and mortality were likely 3-5 times higher. {T}he difference maybe explained by treatment seeking behaviour. {H}owever, incidences and mortalities reported here reflect the number of patients who attend modern health facilities, giving underestimated figures of the burden of snakebites in sub-{S}aharan {A}frica but realistic current requirements for antivenoms.}, keywords = {{S}nakebite ; {E}nvenoming ; {E}pidemiology ; {S}ub-{S}aharan {A}frica}, booktitle = {}, journal = {{T}oxicon}, volume = {57}, numero = {4}, pages = {586--599}, ISSN = {0041-0101}, year = {2011}, DOI = {10.1016/j.toxicon.2010.12.022}, URL = {https://www.documentation.ird.fr/hor/fdi:010053448}, }