@article{fdi:010053418,
  title = {{P}roduction of viable gametes without meiosis in maize deficient for an {ARGONAUTE} protein},
  author = {{S}ingh, {M}anjit and {G}oel, {S}halendra and {M}eeley, {R}.{B}. and {D}antec, {C}. and {P}arrinello, {H}. and {M}ichaud, {C}aroline and {L}eblanc, {O}livier and {G}rimanelli, {D}aniel},
  editor = {},
  language = {{ENG}},
  abstract = {{A}pomixis is a form of asexual reproduction through seeds in angiosperms. {A}pomictic plants bypass meiosis and fertilization, developing offspring that are genetically identical to their mother. {I}n a genetic screen for maize ({Z}ea mays) mutants mimicking aspects of apomixis, we identified a dominant mutation resulting in the formation of functional unreduced gametes. {T}he mutant shows defects in chromatin condensation during meiosis and subsequent failure to segregate chromosomes. {T}he mutated locus codes for {AGO}104, a member of the {ARGONAUTE} family of proteins. {AGO}104 accumulates specifically in somatic cells surrounding the female meiocyte, suggesting a mobile signal rather than cell-autonomous control. {AGO}104 is necessary for non-{CG} methylation of centromeric and knob-repeat {DNA}. {D}igital gene expression tag profiling experiments using high-throughput sequencing show that {AGO}104 influences the transcription of many targets in the ovaries, with a strong effect on centromeric repeats. {AGO}104 is related to {A}rabidopsis thaliana {AGO}9, but while {AGO}9 acts to repress germ cell fate in somatic tissues, {AGO}104 acts to repress somatic fate in germ cells. {O}ur findings show that female germ cell development in maize is dependent upon conserved small {RNA} pathways acting non-cell-autonomously in the ovule. {I}nterfering with this repression leads to apomixis-like phenotypes in maize.},
  keywords = {},
  booktitle = {},
  journal = {{P}lant {C}ell},
  volume = {23},
  numero = {2},
  pages = {443--458},
  ISSN = {1040-4651},
  year = {2011},
  DOI = {10.1105/tpc.110.079020},
  URL = {https://www.documentation.ird.fr/hor/fdi:010053418},
}