@article{fdi:010053380, title = {{H}igh {HIV} type 1 group {M} pol diversity and low rate of antiretroviral resistance mutations among the uniformed services in {K}inshasa, {D}emocratic {R}epublic of the {C}ongo}, author = {{D}joko, {C}. {F}. and {R}imoin, {A}. {W}. and {V}idal, {N}icole and {T}amoufe, {U}. and {W}olfe, {N}. {D}. and {B}utel, {C}hristelle and {L}e{B}reton, {M}. and {T}shala, {F}. {M}. and {K}ayembe, {P}. {K}. and {M}uyembe, {J}. {J}. and {E}didi-{B}asepeo, {S}. and {P}ike, {B}. {L}. and {F}air, {J}. {N}. and {M}bacham, {W}. {F}. and {S}aylors, {K}. {E}. and {M}poudi-{N}gole, {E}. and {D}elaporte, {E}ric and {G}rillo, {M}. and {P}eeters, {M}artine}, editor = {}, language = {{ENG}}, abstract = {{F}or the first time the genetic diversity among the uniformed personnel in {K}inshasa, the capital city of the {D}emocratic {R}epublic of {C}ongo ({DRC}), a country that has experienced military conflicts since 1998 and in which the global {HIV}-1/{M} pandemic started, has now been documented. {A} total of 94 {HIV}-1-positive samples, collected in 2007 in {K}inshasa garrison settings from informed consenting volunteers, were genetically characterized in the pol region (protease and {RT}). {A}n extensive diversity was observed, with 51% of the strains corresponding to six pure subtypes ({A} 23%, {C} 13.8%, {D}, {G}, {H}, {J}, and untypable), 15% corresponding to nine different {CRF}s (01, 02, 11, 13, 25, 26, 37, 43, and 45), and 34% being unique recombinants with one-third being complex mosaic viruses involving three or more different subtypes/{CRF}s. {O}nly one strain harbored a single mutation, {I}54{V}, associated with drug resistance to protease inhibitors. {D}ue to their high mobility and potential risk behavior, {HIV} infections in military personnel can lead to an even more complex epidemic in the {DRC} and to a possible increase of subtype {C}.}, keywords = {}, booktitle = {}, journal = {{A}ids {R}esearch and {H}uman {R}etroviruses}, volume = {27}, numero = {3}, pages = {323--329}, ISSN = {0889-2229}, year = {2011}, DOI = {10.1089/aid.2010.0201}, URL = {https://www.documentation.ird.fr/hor/fdi:010053380}, }