@article{fdi:010053359, title = {{A} fresh look at the origin of {P}lasmodium falciparum, the most malignant malaria agent}, author = {{P}rugnolle, {F}ranck and {D}urand, {P}atrick and {O}llomo, {B}. and {D}uval, {L}inda and {A}riey, {F}. and {A}rnathau, {C}{\'e}line and {G}onzalez, {J}ean-{P}aul and {L}eroy, {E}ric and {R}enaud, {F}rancois}, editor = {}, language = {{ENG}}, abstract = {{F}rom which host did the most malignant human malaria come: birds, primates, or rodents? {W}hen did the transfer occur? {O}ver the last half century, these have been some of the questions up for debate about the origin of {P}lasmodium falciparum, the most common and deadliest human malaria parasite, which is responsible for at least one million deaths every year. {R}ecent findings bring elements in favor of a transfer from great apes, but are these evidences really solid? {W}hat are the grey areas that remain to be clarified? {H}ere, we examine in depth these new elements and discuss how they modify our perception of the origin and evolution of {P}. falciparum. {W}e also discuss the perspectives these new discoveries open.}, keywords = {}, booktitle = {}, journal = {{P}los {P}athogens}, volume = {7}, numero = {2}, pages = {e1001283}, ISSN = {1553-7366}, year = {2011}, DOI = {10.1371/journal.ppat.1001283}, URL = {https://www.documentation.ird.fr/hor/fdi:010053359}, }