Faye B. auteur aut IRD Banuls Anne-Laure auteur aut IRD Bucheton Bruno auteur aut IRD Dione M. M. auteur aut IRD Bassanganam O. auteur aut IRD Hide Mallorie auteur aut IRD Dereure J. auteur aut IRD Choisy Marc auteur aut IRD Ndiaye J. L. auteur aut IRD Konate O. auteur aut IRD Claire M. auteur aut IRD Senghor M. W. auteur aut IRD Faye M. N. auteur aut IRD Sy I. auteur aut IRD Niang A. A. auteur aut IRD Molez Jean-François auteur aut IRD Victoir K. auteur aut IRD Marty P. auteur aut IRD Delaunay P. auteur aut IRD Knecht R. auteur aut IRD Mellul S. auteur aut IRD Diedhiou S. auteur aut IRD Gaye O. auteur aut IRD text journalArticle eng text/pdf born digital access In the context of global warming and the risk of spreading arthropod-borne diseases, the emergence and reemergence of leishmaniasis should not be neglected. In Senegal, over the past few years, cases of canine leishmaniasis have been observed. We aim to improve the understanding of the transmission cycle of this zoonosis, to determine the responsible species and to evaluate the risk for human health. An epidemiological and serological study on canine and human populations in the community of Mont Rolland (Thies area) was conducted. The data showed a high seroprevalence of canine leishmaniasis (>40%) and more than 30% seropositive people. The dogs' seroprevalence was confirmed by PCR data (concordance > 0.85, Kappa > 0.7). The statistical analysis showed strong statistical associations between the health status of dogs and seropositivity, the number of positive PCRs, clinical signs and the number of Leishmania isolates. For the first time, the discriminative PCRs performed on canine Leishmania strains clearly evidenced that the pathogenic agent is Leishmania infantum. The results obtained show that transmission of this species is well established in this area. That the high incidence of seropositivity in humans may be a consequence of infection with this species is discussed. Published by Elsevier Masson SAS on behalf of the Institut Pasteur. specialized Leishmania infantum Human Dog West Africa Prevalence 052 12 14-15 1219-1225 2010 1286-4579 https://www.documentation.ird.fr/hor/fdi:010053357 10.1016/j.micinf.2010.09.003 1286-4579 [F B010053357] https://www.documentation.ird.fr/hor/fdi:010053357 https://www.documentation.ird.fr/intranet/publi/2011/03/010053357.pdf Accès réservé (Intranet de l'IRD) IRD - Base Horizon / Pleins textes 2011-04-07 2017-08-23 fdi:010053357 fre