@article{fdi:010053357, title = {{C}anine visceral leishmaniasis caused by {L}eishmania infantum in {S}enegal : risk of emergence in humans ?}, author = {{F}aye, {B}. and {B}anuls, {A}nne-{L}aure and {B}ucheton, {B}runo and {D}ione, {M}. {M}. and {B}assanganam, {O}. and {H}ide, {M}allorie and {D}ereure, {J}. and {C}hoisy, {M}arc and {N}diaye, {J}. {L}. and {K}onate, {O}. and {C}laire, {M}. and {S}enghor, {M}. {W}. and {F}aye, {M}. {N}. and {S}y, {I}. and {N}iang, {A}. {A}. and {M}olez, {J}ean-{F}ran{\c{c}}ois and {V}ictoir, {K}. and {M}arty, {P}. and {D}elaunay, {P}. and {K}necht, {R}. and {M}ellul, {S}. and {D}iedhiou, {S}. and {G}aye, {O}.}, editor = {}, language = {{ENG}}, abstract = {{I}n the context of global warming and the risk of spreading arthropod-borne diseases, the emergence and reemergence of leishmaniasis should not be neglected. {I}n {S}enegal, over the past few years, cases of canine leishmaniasis have been observed. {W}e aim to improve the understanding of the transmission cycle of this zoonosis, to determine the responsible species and to evaluate the risk for human health. {A}n epidemiological and serological study on canine and human populations in the community of {M}ont {R}olland ({T}hies area) was conducted. {T}he data showed a high seroprevalence of canine leishmaniasis (>40%) and more than 30% seropositive people. {T}he dogs' seroprevalence was confirmed by {PCR} data (concordance > 0.85, {K}appa > 0.7). {T}he statistical analysis showed strong statistical associations between the health status of dogs and seropositivity, the number of positive {PCR}s, clinical signs and the number of {L}eishmania isolates. {F}or the first time, the discriminative {PCR}s performed on canine {L}eishmania strains clearly evidenced that the pathogenic agent is {L}eishmania infantum. {T}he results obtained show that transmission of this species is well established in this area. {T}hat the high incidence of seropositivity in humans may be a consequence of infection with this species is discussed. {P}ublished by {E}lsevier {M}asson {SAS} on behalf of the {I}nstitut {P}asteur.}, keywords = {{L}eishmania infantum ; {H}uman ; {D}og ; {W}est {A}frica ; {P}revalence}, booktitle = {}, journal = {{M}icrobes and {I}nfection}, volume = {12}, numero = {14-15}, pages = {1219--1225}, ISSN = {1286-4579}, year = {2010}, DOI = {10.1016/j.micinf.2010.09.003}, URL = {https://www.documentation.ird.fr/hor/fdi:010053357}, }