@article{fdi:010053139,
  title = {{E}fficacy of an insecticide paint against malaria vectors and nuisance in {W}est {A}frica - {P}art 2 : {F}ield evaluation},
  author = {{M}osqueira, {B}. and {C}habi, {J}oseph and {C}handre, {F}abrice and {A}kogbeto, {M}. and {H}ougard, {J}ean-{M}arc and {C}arnevale, {P}ierre and {M}as-{C}oma, {S}.},
  editor = {},
  language = {{ENG}},
  abstract = {{B}ackground: {W}idespread resistance of the main malaria vector {A}nopheles gambiae to pyrethroids reported in many {A}frican countries and operational drawbacks to current {IRS} methods suggest the convenience of exploring new products and approaches for vector control. {I}nsecticide paint {I}nesfly 5{A} {IGR} ({TM}), containing two organophosphates ({OP}s), chlorpyrifos and diazinon, and one insect growth regulator ({IGR}), pyriproxyfen, was tested in {B}enin, {W}est {A}frica, for 12 months. {M}ethods: {F}ield trials were conducted in six experimental huts that were randomly allocated to one or two layers of insecticide at 1 {K}g/6 m(2) or control. {E}valuations included: (i) early mosquito collection, (ii) mosquito release experiments, (iii) residual efficacy tests and (iv) distance tests. {E}arly mosquito collections were performed on local populations of pyrethroid-resistant {A}n. gambiae and {C}ulex quinquefasciatus. {A}s per {WHOPES} phase {II} procedures, four entomological criteria were evaluated: deterrence, excito-repellence, blood-feeding inhibition and mortality. {M}osquito release experiments were done using local malaria-free {A}n. gambiae females reared at the {CREC} insectarium. {R}esidual efficacy tests and distance tests were performed using reference susceptible strains of {A}n. gambiae and {C}x. quinquefasciatus. {R}esults: {S}ix months after treatment, mortality rates were still 90-100% against pyrethroid-resistant mosquito populations in experimental huts. {A}t nine months, mortality rates in huts treated with two layers was still about 9093% against {A}n. gambiae and 55% against {C}x. quinquefasciatus. {M}alaria-free local mosquito release experiments yielded a 90% blood-feeding inhibition in the absence of a physical barrier. {A} long-term residual efficacy of 12 months was observed by {WHO}-bioassays in huts treated with two layers (60-80%). {M}ortality after an overnight exposition at distances of 1 meter was 96-100% for up to 12 months. {C}onclusion: {T}he encouraging results obtained on the insecticide paint {I}nesfly 5{A} {IGR} {T} in terms of mortality, be it in direct contact or at a distance, and its new operational approach could constitute an additional option in malaria control efforts in areas of pyrethroid resistance. {P}hase {III} studies will be performed to assess the product's epidemiological impact and sociological acceptance.},
  keywords = {},
  booktitle = {},
  journal = {{M}alaria {J}ournal},
  volume = {9},
  numero = {},
  pages = {341},
  ISSN = {1475-2875},
  year = {2010},
  DOI = {10.1186/1475-2875-9-341},
  URL = {https://www.documentation.ird.fr/hor/fdi:010053139},
}