@article{fdi:010053065,
  title = {{N}o evidence for transmission of {SIV}wrc from western red colobus monkeys (piliocolobus badius badius) to wild west african chimpanzees (pan troglodytes verus) despite high exposure through hunting},
  author = {{L}eendertz, {S}. {A}. {J}. and {L}ocatelli, {S}abrina and {B}oesch, {C}. and {K}ucherer, {C}. and {F}ormenty, {P}. and {L}i{\'e}geois, {F}lorian and {A}youba, {A}hidjo and {P}eeters, {M}artine and {L}eendertz, {F}. {H}.},
  editor = {},
  language = {{ENG}},
  abstract = {{B}ackground: {S}imian {I}mmunodeficiency {V}iruses ({SIV}s) are the precursors of {H}uman {I}mmunodeficiency {V}iruses ({HIV}s) which have lead to the worldwide {HIV}/{AIDS} pandemic. {B}y studying {SIV}s in wild primates we can better understand the circulation of these viruses in their natural hosts and habitat, and perhaps identify factors that influence susceptibility and transmission within and between various host species. {W}e investigated the {SIV} status of wild {W}est {A}frican chimpanzees ({P}an troglodytes verus) which frequently hunt and consume the western red colobus monkey ({P}iliocolobus badius badius), a species known to be infected to a high percentage with its specific {SIV} strain ({SIV}wrc). {R}esults: {B}lood and plasma samples from 32 wild chimpanzees were tested with {INNO}-{LIA} {HIV} {I}/{II} {S}core kit to detect cross-reactive antibodies to {HIV} antigens. {T}wenty-three of the samples were also tested for antibodies to 43 specific {SIV} and {HIV} lineages, including {SIV}wrc. {T}issue samples from all but two chimpanzees were tested for {SIV} by {PCR}s using generic {SIV} primers that detect all known primate lentiviruses as well as primers designed to specifically detect {SIV}wrc. {S}eventeen of the chimpanzees showed varying degrees of cross-reactivity to the {HIV} specific antigens in the {INNO}-{LIA} test; however no sample had antibodies to {SIV} or {HIV} strain - and lineage specific antigens in the {L}uminex test. {N}o {SIV} {DNA} was found in any of the samples. {C}onclusions: {W}e could not detect any conclusive trace of {SIV} infection from the red colobus monkeys in the chimpanzees, despite high exposure to this virus through frequent hunting. {T}he results of our study raise interesting questions regarding the host-parasite relationship of {SIV}wrc and wild chimpanzees in their natural},
  keywords = {},
  booktitle = {},
  journal = {{B}mc {M}icrobiology},
  volume = {11},
  numero = {},
  pages = {24},
  ISSN = {1471-2180},
  year = {2011},
  DOI = {10.1186/1471-2180-11-24},
  URL = {https://www.documentation.ird.fr/hor/fdi:010053065},
}