@article{fdi:010053064,
  title = {{H}igh efficacy of anti {DBL}4 epsilon-{VAR}2{CSA} antibodies in inhibition of {CSA}-binding {P}lasmodium falciparum-infected erythrocytes from pregnant women},
  author = {{M}agistrado, {P}. {A}. and {M}inja, {D}. and {D}oritchamou, {J}. and {T}uikue {N}dam, {N}icaise and {J}ohn, {D}. and {S}chmiegelow, {C}. and {M}assougbodji, {A}. and {D}ahlback, {M}. and {D}itlev, {S}. {B}. and {P}into, {V}. {V}. and {R}esende, {M}. and {L}usingu, {J}. and {T}heander, {T}. {G}. and {S}alanti, {A}. and {N}ielsen, {M}. {A}.},
  editor = {},
  language = {{ENG}},
  abstract = {{M}alaria during pregnancy is a major cause of intra-uterine growth-retardation and infant death in sub-{S}aharan {A}frica. {I}deally, this could be prevented by a vaccine delivered before the first pregnancy. {A}ntibodies against domain {DBL}4 epsilon from {VAR}2{CSA} has been shown to inhibit adhesion of laboratory isolates to the placental receptor chondroitin sulfate {A}. {I}n this study, the binding inhibitory efficacy of {I}g{G} elicited by two different {DBL}4 epsilon recombinant proteins was tested on a panel of fresh clinical isolates from pregnant women living in {B}enin and {T}anzania. {T}he most promising recombinant protein elicited antibodies with similar efficacy as pooled plasma from immune multi-gravid {A}frican women.},
  keywords = {{P}lacental malaria ; {VAR}2{CSA} ; {V}accine ; {P}lasmodium falciparum},
  booktitle = {},
  journal = {{V}accine},
  volume = {29},
  numero = {3},
  pages = {437--443},
  ISSN = {0264-410{X}},
  year = {2011},
  DOI = {10.1016/j.vaccine.2010.10.080},
  URL = {https://www.documentation.ird.fr/hor/fdi:010053064},
}