@article{fdi:010053000,
  title = {{G}enetic basis of pearl millet adaptation along an environmental gradient investigated by a combination of genome scan and association mapping},
  author = {{M}ariac, {C}{\'e}dric and {J}ehin, {L}. and {S}aidou, {A}bdoul-{A}ziz and {T}huillet, {A}nne-{C}{\'e}line and {C}ouderc, {M}. and {S}ire, {P}. and {J}ugde, {H}. and {A}dam, {H}{\'e}l{\`e}ne and {B}ezan{\c{c}}on, {G}illes and {P}ham, {J}ean-{L}ouis and {V}igouroux, {Y}ves},
  editor = {},
  language = {{ENG}},
  abstract = {{I}dentifying the molecular bases of adaptation is a key issue in evolutionary biology. {G}enome scan is an efficient approach for identifying important molecular variation involved in adaptation. {A}ssociation mapping also offers an opportunity to gain insight into genotype-phenotype relationships. {U}sing these two approaches coupled with environmental data should help to come up with a refined picture of the evolutionary process underlying adaptation. {I}n this study, we first conducted a selection scan analysis on a transcription factor gene family. {W}e focused on the {MADS}-box gene family, a gene family which plays a crucial role in vegetative and flower development. {T}wenty-one pearl millet populations were sampled along an environmental gradient in {W}est {A}frica. {W}e identified one gene, i.e. {P}g{MADS}11, using {B}ayesian analysis to detect selection signatures. {P}olymorphism at this gene was also associated with flowering time variation in an association mapping framework. {F}inally, we found that {P}g{MADS}11 allele frequencies were closely associated with annual rainfall. {O}verall, we determined an efficient way to detect functional polymorphisms associated with climate variation in non-model plants by combining genome scan and association mapping. {T}hese results should help monitor the impact of recent climatic changes on plant adaptation.},
  keywords = {adaptation ; flowering time ; genome scan ; {MADS}-box genes ; {P}ennisetum ; glaucum},
  booktitle = {},
  journal = {{M}olecular {E}cology},
  volume = {20},
  numero = {1},
  pages = {80--91},
  ISSN = {0962-1083},
  year = {2011},
  DOI = {10.1111/j.1365-294{X}.2010.04893.x},
  URL = {https://www.documentation.ird.fr/hor/fdi:010053000},
}