@article{fdi:010052981, title = {{C}omplementary foods fortified with micronutrients prevent iron deficiency and anemia in {V}ietnamese infants}, author = {{P}ham, {V}. {P}. and {N}guyen, {V}. {H}. and {S}alvignol, {B}. and {T}r{\`e}che, {S}erge and {W}ieringa, {F}ranck and {N}guyen, {C}. {K}. and {P}ham, {D}. {T}. and {B}erger, {J}acques}, editor = {}, language = {{ENG}}, abstract = {{T}o investigate whether an intervention including micronutnent-fortified complementary foods can improve iron status we conducted a randomized controlled trial in 5 mo-old {V}ietnamese infants (n = 246) {V}illages (n = 29) were randomly divided into those receiving instant flour {IFF}) or a food complement ({FC}) both fortified with micronutrients or nothing [control ({C})] {FF} and {FC} infants received daily for 6 mo at least 2 meals of fortified complementary foods {M}icronutrient status was assessed by measurement of hemoglobin ({H}b) and plasma ferritin ({PF}) transferrin receptor zinc and retinol {F}inal {H}b (mean +/- {SD}) was higher in the {FF} (112 5 +/- 8 0 g/{L}) and {FC} (114 0 +/- 7 0 g/{L}) groups compared with {C} (109 0 +/- 8 0 g/{L} {P}= 0 006) {PF} (geometric mean [95% {C}l]) was also higher in {FF} (19 8 mu g/{L} [17 5-22 31] and {FC} (20 8 mu g/{L} [18 3-23 61]) compared with {C} (11 1 mu g/{L} [98-12 5] {P} < 00001) {A}nemia prevalence decreased more in the {FC} group (-43 6%) compared with {C} (-10 3% {P}= 0 006) {T}he change in prevalence of {PF} < 12 mu g/{L} was different in the {FF}(-16 4%) and {FC} (-6 7%) groups compared with {C} (+30 4% {P} < 0 01) {E}ndpoint prevalence of iron deficiency ({ID}) and {ID} anemia ({IDA}) were lower in the {FF} (13 4 and 6 7% respectively) and {FC} (15 2 and 3 8%) groups compared with {C} (57 5 and 37 5%) ({P}< 0 0001) {R}etinol and zinc concentrations did not differ among groups but endpoint prevalence of zinc deficiency was lower in {FF} infants (36 1%) than in {C} infants (52 9% {P} = 0 04) {M}icronument-fortified complementary foods significantly improved iron status and decreased the prevalence of anemia {ID}, and {IDA} in {V}ietnamese infants and can be an important tool to reduce {ID} in infancy in developing countries {J} {N}utr 140 2241-2247, 2010}, keywords = {}, booktitle = {}, journal = {{J}ournal of {N}utrition}, volume = {140}, numero = {12}, pages = {2241--2247}, ISSN = {0022-3166}, year = {2010}, DOI = {10.3945/jn.110.123711}, URL = {https://www.documentation.ird.fr/hor/fdi:010052981}, }