@article{fdi:010052951, title = {{T}he adaptation of {R}ice yellow mottle virus to the e{IF}(iso)4{G}-mediated rice resistance}, author = {{T}raor{\'e}, {O}. and {P}inel {G}alzi, {A}gn{\`e}s and {I}ssaka, {S}. and {P}oulicard, {N}ils and {A}ribi, {J}amel and {A}k{\'e}, {S}. and {G}hesqui{\`e}re, {A}lain and {S}{\'e}r{\'e}, {Y}. and {K}onat{\'e}, {G}. and {H}{\'e}brard, {E}ug{\'e}nie and {F}argette, {D}enis}, editor = {}, language = {{ENG}}, abstract = {{T}he rymv1-3 allele of the e{IF}(iso)4{G}-mediated resistance to {R}ice yellow mottle virus ({RYMV}) is found in a few {O}ryza glaberrima cultivars. {T}he same resistance-breaking ({RB}) mutations emerged in the central domain of the {VP}g after inoculation of isolates of different strains. {T}he {RB} mutations were fixed, often sequentially, at codons 41 and 52 which paralleled an increase in virus accumulation. {RB} mutations also emerged after inoculation of an avirulent infectious clone, indicating that they were generated de novo in resistant plants. {O}nly virus isolates with a threonine at codon 49 of the {VP}g broke rymv1-3 resistance, those with a glutamic acid did not {A} small subset of these isolates overcame rymv1-2 resistance, but following a specific pathway. {C}omparison with the {RB} process of rymv1-2, a resistance allele found in a few {O}ryza sativa cultivars, showed similarities in the mode of adaptation but revealed converse virulence specificity of the isolates.}, keywords = {{P}lant resistance ; {R}esistance breakdown ; {V}irus adaptation ; {V}irus evolution}, booktitle = {}, journal = {{V}irology}, volume = {408}, numero = {1}, pages = {103--108}, ISSN = {0042-6822}, year = {2010}, DOI = {10.1016/j.virol.2010.09.007}, URL = {https://www.documentation.ird.fr/hor/fdi:010052951}, }