%0 Journal Article
%9 ACL : Articles dans des revues avec comité de lecture répertoriées par l'AERES
%A Brutus, Laurent
%A Castillo, H.
%A Bernal, C.
%A Salas, N. A.
%A Schneider, Dominique
%A Santalla, J. A.
%A Chippaux, Jean-Philippe
%T Detectable Trypanosoma cruzi parasitemia during pregnancy and delivery as a risk factor for congenital Chagas disease : short report
%D 2010
%L fdi:010052914
%G ENG
%J American Journal of Tropical Medicine and Hygiene
%@ 0002-9637
%M ISI:000284184600017
%N 5
%P 1044-1047
%R 10.4269/ajtmh.2010.10.0326
%U https://www.documentation.ird.fr/hor/fdi:010052914
%> https://horizon.documentation.ird.fr/exl-doc/pleins_textes/divers20-08/010052914.pdf
%V 83
%W Horizon (IRD)
%X Vector control has led to a drastic decrease in the prevalence of acquired Chagas disease in Latin America thus redirecting attention to congenital Chagas disease We report results of a longitudinal study of 359 pregnant women in Yacuiba in southern Bolivia, of whom 147 (40 9%) were infected with Trypanosoma cruzi, to evaluate the relation ship between the patency period of the parasitemia and the risk of congenital infection Maternal infection was assessed by using T cruzi-specific serologic tests and parasitemia in mothers and newborns was diagnosed by using microscopic examination of blood in heparinized microhematocrit tubes Parasitemia was present in 28 6% of the infected women Its prevalence increased during the third trimester then decreased at delivery The likelihood of congenital infection was significantly correlated with the parasite density in the mother s blood The risk of transmission increased during the third trimester of pregnancy and could explain premature births or low weight newborns for infected mothers
%$ 052