@article{fdi:010052843,
  title = {{F}ield evaluation of pyriproxyfen and spinosad mixture for the control of insecticide resistant {A}edes aegypti in {M}artinique ( {F}rench {W}est {I}ndies)},
  author = {{D}arriet, {F}r{\'e}d{\'e}ric and {M}arcombe, {S}{\'e}bastien and {E}tienne, {M}. and {Y}ebakima, {A}ndr{\'e} and {A}gnew, {P}hilip and {Y}p-{T}cha, {M}. {M}. and {C}orbel, {V}incent},
  editor = {},
  language = {{ENG}},
  abstract = {{B}ackground: {T}he resistance of {A}e. aegypti to insecticides is already widespread and continues to develop. {I}t represents a serious problem for programmes aimed at the control and prevention of dengue in tropical countries. {I}n the light of this problem measures to control {A}e. aegypti are being orientated towards how best to use existing insecticides, notably by combining those that have different modes of action. {R}esults: {I}n this study we evaluated the operational efficiency of a mixture composed of pyriproxyfen (an insect growth regulator) and spinosad (a biopesticide) against a population of {A}e. aegypti from {M}artinique resistant to pyrethroid and organophosphate insecticides. {T}he first step consisted of evaluating the efficacy of pyriproxyfen and spinosad when used alone, or in combination, against {A}e. aegypti larvae under simulated conditions. {T}he results showed that the mixture of pyriproxyfen+spinosad remained active for at least 8 months, compared with 3 months for spinosad alone, and 5 months for pyriproxyfen alone. {I}n a second step in containers experiencing natural conditions, pyriproxyfen and spinosad, maintained the rate of adult emergence at 20% for 3 weeks and 3.5 months, respectively. {F}ollowing the same criteria of evaluation, the mixture pyriproxyfen+spinosad remained effective for 4.5 months, showing that the combination of the two larvicides with different modes of action acted to increase the residual activity of the treatment. {C}onclusion: {T}he mixture of pyriproxyfen and spinosad kills larvae and pupae giving it a broader range of action than either insecticide. {T}his mixture could preserve the utility of both insecticides in public health programs.},
  keywords = {{MARTINIQUE}},
  booktitle = {},
  journal = {{P}arasites and {V}ectors},
  volume = {3},
  numero = {},
  pages = {88},
  ISSN = {1756-3305},
  year = {2010},
  DOI = {10.1186/1756-3305-3-88},
  URL = {https://www.documentation.ird.fr/hor/fdi:010052843},
}