@article{fdi:010052477,
  title = {{C}haracteristics of {HIV} type 1 ({HIV}-1) glycoprotein 120 env sequences in mother-infant pairs infected with {HIV}-1 subtype {CRF}01_{AE}},
  author = {{S}amleerat, {T}. and {B}raibant, {M}. and {J}ourdain, {G}onzague and {M}oreau, {A}. and {N}go-{G}iang-{H}uong, {N}icole and {L}eechanachai, {P}. and {H}emvuttiphan, {J}. and {H}injiranandana, {T}. and {C}hangchit, {T}. and {W}arachit, {B}. and {S}uraseranivong, {V}. and {L}allemant, {M}arc and {B}arin, {F}.},
  editor = {},
  language = {{ENG}},
  abstract = {{W}e analyzed the characteristics of the envelope genes of human immunodeficiency virus type 1 in 17 mother-infant pairs infected with variants of the {CRF}01_ {AE} clade. {A} total of 353 sequences covering almost the entire glycoprotein (gp) 120 region were available for analysis. {W}e found that, even if the virus population in the mother was complex, only viruses of a restricted subset were transmitted to her infant, independently of whether transmission occurred in utero or during the intrapartum period. {W}e did not find that shorter gp120 regions or fewer potential {N}- glycosylation sites({PNGS}) were characteristic of viruses transmitted from mother to infant. {H}owever, our data suggest that a limited number of {PNGS} that seem to be conserved in all variants in infants but are not uniformly present in variants in mothers may confer an advantage for transmission of the virus, thereby highlighting the potentially important role of the " glycan shield." {T}his finding was particularly significant for the {PNGS} at positions {N}301 and {N}384.},
  keywords = {},
  booktitle = {},
  journal = {{J}ournal of {I}nfectious {D}iseases},
  volume = {198},
  numero = {6},
  pages = {868--876},
  ISSN = {0022-1899},
  year = {2008},
  DOI = {10.1086/591251},
  URL = {https://www.documentation.ird.fr/hor/fdi:010052477},
}