%0 Journal Article
%9 ACL : Articles dans des revues avec comité de lecture répertoriées par l'AERES
%A Coates, J. C.
%A Laplaze, L.
%A Haseloff, J.
%T Armadillo-related proteins promote lateral root development in Arabidopsis
%D 2006
%L fdi:010052290
%G ENG
%J Proceedings of the National Academy of Sciences of the United States of America
%K plant ; beta catenin ; arabidillo
%M CC:0002350943-0083
%N 5
%P 1621-1626
%R 10.1073/pnas.0507575103
%U https://www.documentation.ird.fr/hor/fdi:010052290
%> https://www.documentation.ird.fr/intranet/publi/depot/2011-07-27/010052290.pdf
%V 103
%W Horizon (IRD)
%X lArmadillo/beta-catenin and related proteins have important functions during animal and Dictyostelium development, regulating cell differentiation, proliferation, and adhesion. Armadillo-repeat-containing proteins also exist in plants, but the majority have unknown roles. The Arabidopsis genes that show greatest sequence homology to Armadillo/beta-catenin are called ARABIDILLO-1 and -2. Here, we demonstrate that ARABIDILLO-1 and -2 promote lateral root development. arabidillo-1/-2 mutants form fewer lateral roots, and ARABIDILLO-1-overexpressing lines produce more lateral roots than wild-type seedlings. ARABIDILLO-yellow fluorescent protein fusions are nuclear. ARABIDILLO proteins contain an F-box motif, and thus may target other proteins for proteasomal degradation. Overexpression of ARABIDILLO-1 protein fragments, including F-box fragments, in wild-type seedlings reduces lateral root formation to the level of the arabidillo-1/-2 mutant. We have shown that plant beta-catenin-related proteins regulate root development. We suggest that ARABIDILLO proteins may target an inhibitor of lateral root development for degradation and propose that Arabidopsis 13-catenin-related proteins define a previously uncharacterized pathway that promotes root branching.