@article{fdi:010052290, title = {{A}rmadillo-related proteins promote lateral root development in {A}rabidopsis}, author = {{C}oates, {J}. {C}. and {L}aplaze, {L}. and {H}aseloff, {J}.}, editor = {}, language = {{ENG}}, abstract = {l{A}rmadillo/beta-catenin and related proteins have important functions during animal and {D}ictyostelium development, regulating cell differentiation, proliferation, and adhesion. {A}rmadillo-repeat-containing proteins also exist in plants, but the majority have unknown roles. {T}he {A}rabidopsis genes that show greatest sequence homology to {A}rmadillo/beta-catenin are called {ARABIDILLO}-1 and -2. {H}ere, we demonstrate that {ARABIDILLO}-1 and -2 promote lateral root development. arabidillo-1/-2 mutants form fewer lateral roots, and {ARABIDILLO}-1-overexpressing lines produce more lateral roots than wild-type seedlings. {ARABIDILLO}-yellow fluorescent protein fusions are nuclear. {ARABIDILLO} proteins contain an {F}-box motif, and thus may target other proteins for proteasomal degradation. {O}verexpression of {ARABIDILLO}-1 protein fragments, including {F}-box fragments, in wild-type seedlings reduces lateral root formation to the level of the arabidillo-1/-2 mutant. {W}e have shown that plant beta-catenin-related proteins regulate root development. {W}e suggest that {ARABIDILLO} proteins may target an inhibitor of lateral root development for degradation and propose that {A}rabidopsis 13-catenin-related proteins define a previously uncharacterized pathway that promotes root branching.}, keywords = {plant ; beta catenin ; arabidillo}, booktitle = {}, journal = {{P}roceedings of the {N}ational {A}cademy of {S}ciences of the {U}nited {S}tates of {A}merica}, volume = {103}, numero = {5}, pages = {1621--1626}, year = {2006}, DOI = {10.1073/pnas.0507575103}, URL = {https://www.documentation.ird.fr/hor/fdi:010052290}, }