@article{fdi:010052120,
  title = {{I}dentification and molecular characterization of subsubtype {A}4 in {C}entral {A}frica},
  author = {{V}idal, {N}icole and {M}ulanga, {C}laire and {B}azepeo, {S}.{E}. and {L}epira, {F}. and {D}elaporte, {E}ric and {P}eeters, {M}artine},
  editor = {},
  language = {{ENG}},
  abstract = {{P}hylogenetic analysis on partial env sequences of {HIV}-1-positive samples obtained from sentinel population groups in {HIV} serosurveillance studies in 1997 and 2002 in the {D}emocratic {R}epublic of {C}ongo ({DRC}) revealed a high genetic diversity in the number of cocirculating subtypes/{CRF}s as well as intrasubtype diversity. {A} cluster of three strains that formed a distinct and well-separated group within the subtype {A} radiation was observed. {T}o determine a more precise structure of these viruses, the full-length genomes were sequenced. {P}hylogenetic tree and bootscan analysis showed that all three newly characterized viruses formed a new nonrecombinant lineage that was more closely related to subtype {A}. {T}he {SUDI} ({S}ubtype {D}istance) program showed that the distances of the newly derived {HIV}-1 sequences to subtype {A} references fell in the range of distances previously characterized for subsubtypes. {A}ccording to current nomenclature rules, we have thus designated this new lineage as subsubtype {A}4. {A}nalysis of viral sequences from other {A}frican countries suggests that the {A}4 strains seem restricted to {DRC} where they already circulated at the onset of the {HIV}/{AIDS} epidemic.},
  keywords = {{CENTRAFRIQUE}},
  booktitle = {},
  journal = {{A}ids {R}esearch and {H}uman {R}etroviruses},
  volume = {22},
  numero = {2},
  pages = {182--187},
  year = {2006},
  DOI = {10.1089/aid.2006.22.182},
  URL = {https://www.documentation.ird.fr/hor/fdi:010052120},
}