@article{fdi:010052093, title = {{E}valuation of the antibody response to {A}nopheles salivary antigens as a potential marker of risk of malaria}, author = {{R}emou{\'e}, {F}ranck and {C}isse, {B}. and {B}a, {F}.{T}. and {S}okhna, {C}. and {H}erve, {J}ean-{P}ierre and {B}oulanger, {D}enis and {S}imondon, {F}ran{\c{c}}ois}, editor = {}, language = {{ENG}}, abstract = {{T}he evaluation of human immune responses to arthropod bites may be a useful marker of exposure to vector-borne diseases, with applications to malaria, the most serious parasitic infection in humans. {T}he specific antibody ({A}b) {I}g{G} response to saliva obtained from {A}nopheles gambiae mosquitoes was evaluated in young children from an area of seasonal malaria transmission in {S}enegal. {S}pecific {I}g{G} was higher in children who developed clinical {P}lasmodium falciparum malaria within the 3 months that followed than in those who did not ({P}<0.05), and it increased significantly ({P}<0.0001) with the level of {A}nopheles exposure, as evaluated by conventional entomological methods. {T}hese results suggest that evaluation of antisalivary {A}b responses could be a useful approach for identifying a marker for the risk of malaria transmission. ({C}) 2005 {R}oyal {S}ociety of {T}ropical {M}edicine and {H}ygiene. {P}ublished by {E}lsevier {L}td. {A}ll rights reserved.}, keywords = {malaria ; immunoepidemiology ; {A}nopheles ; exposure ; transmission ; senegal}, booktitle = {}, journal = {{T}ransactions of the {R}oyal {S}ociety of {T}ropical {M}edicine and {H}ygiene}, volume = {100}, numero = {4}, pages = {363--370}, year = {2006}, DOI = {10.1016/j.trstmh.2005.06.032}, URL = {https://www.documentation.ird.fr/hor/fdi:010052093}, }