@article{fdi:010051996, title = {{W}idely varying {SIV} prevalence rates in naturally infected primate species from {C}ameroon}, author = {{A}ghokeng {F}obang, {A}velin and {L}iu, {W}.{M}. and {B}ibollet {R}uche, {F}. and {L}oul, {S}. and {M}poudi {N}gol{\'e}, {E}. and {L}aurent, {C}hristian and {M}wenda, {J}.{M}. and {L}angat, {D}.{K}. and {C}hege, {G}.{K}. and {M}c{C}lure, {H}.{M}. and {D}elaporte, {E}ric and {S}haw, {G}.{M}. and {H}ahn, {B}.{H}. and {P}eeters, {M}artine}, editor = {}, language = {{ENG}}, abstract = {{A}lthough it is now well established that a substantial proportion of wild-living primates in sub-{S}aharan {A}frica harbor {SIV}, no study to date has examined to what extent the various species are naturally infected. {I}n this study, we first describe the development and validation of sensitive and specific {SIV} antibody detection assays representing all major known primate lentiviral lineages on a panel of 207 sera from 11 different primate species with known infection status. {T}he newly developed assays were then used to determine {SIV} prevalence rates in nine primate species native to {C}ameroon. {A}nalysis of 722 sera revealed widely varying prevalence rates, ranging from an apparent absence of {SIV} infection in crested mona (0/70), grey checked (0/36) and agile mangabeys (0/92), to prevalence rates of 3%, 4%, 11%, 27%, 39% and 52% for mustached (6/203), greater spot-nosed (8/193), northern talapoin (3/26), mantled guereza (14/52), {D}e {B}razza's (9/23) and mandrill (14/27) monkeys, respectively. {T}he epidemiology of naturally occurring {SIV} infections is thus more complex than previously appreciated and the various non-human primate hosts seem to differ in their susceptibility to {SIV} infection. {T}he newly developed assays should now permit to define with greater accuracy existing {SIV} reservoirs and associated human zoonotic risk. ({C}) 2005 {E}lsevier {I}nc. {A}ll rights reserved.}, keywords = {{HIV} ; {SIV} ; prevalence ; non human primates ; {C}ameroon}, booktitle = {}, journal = {{V}irology}, volume = {345}, numero = {1}, pages = {174--189}, year = {2006}, DOI = {10.1016/j.virol.2005.09.046}, URL = {https://www.documentation.ird.fr/hor/fdi:010051996}, }