@article{fdi:010050504,
  title = {{D}o distantly related parasites rely on the same proximate factors to alter the behaviour of their hosts ?},
  author = {{P}onton, {F}leur and {L}ef{\`e}vre, {T}hierry and {L}ebarbenchon, {C}amille and {T}homas, {F}. and {L}oxdale, {H}.{D}. and {M}arche, {L}. and {R}enault, {L}. and {P}errot {M}innot, {M}.{J}. and {B}iron, {D}avid},
  editor = {},
  language = {{ENG}},
  abstract = {{P}hylogenetically unrelated parasites often increase the chances of their transmission by inducing similar phenotypic changes in their hosts. {H}owever, it is not known whether these convergent strategies rely on the same biochemical precursors. {I}n this paper, we explored such aspects by studying two gammarid species ({G}ammarus insensibilis and {G}ammarus pulex; {C}rustacea: {A}mphipoda: {G}ammaridae) serving as intermediate hosts in the life cycle of two distantly related parasites: the trematode, {M}icrophallus papillorobustus and the acanthocephalan, {P}olymorphus minutus. {B}oth these parasite species are known to manipulate the behaviour of their amphipod hosts, bringing them towards the water surface, where they are preferentially eaten by aquatic birds (definitive hosts). {B}y studying and comparing the brains of infected {G}. insensibilis and {G}. pulex with proteomics tools, we have elucidated some of the proximate causes involved in the parasite-induced alterations of host behaviour for each system. {P}rotein identifications suggest that altered physiological compartments in hosts can be similar (e.g. immunoneural connexions) or different (e.g. vision process), and hence specific to the host-parasite association considered. {M}oreover, proteins required to alter the same physiological compartment can be specific or conversely common in both systems, illustrating in the latter case a molecular convergence in the proximate mechanisms of manipulation.},
  keywords = {acanthocephalan ; gammarid ; manipulative parasite ; molecular convergence ; proteomics ; trematode},
  booktitle = {},
  journal = {{P}roceedings of the {R}oyal {S}ociety {B} {B}iological {S}ciences},
  volume = {273},
  numero = {1603},
  pages = {2869--2877},
  ISSN = {0962-8452},
  year = {2006},
  DOI = {10.1098/rspb.2006.3654},
  URL = {https://www.documentation.ird.fr/hor/fdi:010050504},
}