@article{fdi:010050149,
  title = {{P}opulation structure of {A}nopheles gambiae in {A}frica},
  author = {{L}ehmann, {T}. and {L}icht, {M}. and {E}lissa, {N}. and {M}aega, {B}.{T}.{A}. and {C}himumbwa, {J}.{M}. and {W}atsenga, {F}.{T}. and {W}ondji, {C}.{S}. and {S}imard, {F}r{\'e}d{\'e}ric and {H}awley, {W}.{A}.},
  editor = {},
  language = {{ENG}},
  abstract = {{T}he population structure of {A}nopheles gambiae in {A}frica was studied using 11 microsatellite loci in 16 samples from 10 countries. {A}ll loci are located outside polymorphic inversions. {H}eterogeneity among loci was detected and two putative outlier loci were removed from analyses aimed at capturing genome-wide patterns. {T}wo main divisions of the gene pool were separated by high differentiation ({FST} > 0.1). {T}he northwestern ({NW}) division included populations from {S}enegal, {G}hana, {N}igeria, {C}ameroon, {G}abon, {D}emocratic {R}epublic of {C}ongo ({DRC}), and western {K}enya. {T}he southeastern ({SE}) division included populations from eastern {K}enya, {T}anzania, {M}alawi, and {Z}ambia. {I}nhospitable environments for {A}. gambiae along the {R}ift {V}alley partly separate these divisions. {R}educed genetic diversity in the {SE} division and results of an analysis based on private alleles support the hypothesis that a recent bottleneck, followed by colonization from the {NW} populations shaped this structure. {I}n the {NW} division, populations possessing the {M} r{DNA} genotype appeared to form a monophyletic clade. {A}lthough genetic distance increased with geographic distance, discontinuities were suggested between certain sets of populations. {T}he absence of heterozygotes between sympatric {M} and {S} populations in the {DRC} and the high differentiation in locus 678 (⁠{FST} > 0.28) contrasted with low differentiation in all other loci (⁠ -0.02 < {FST} < 0.09⁠) and with the persistence of departures from {H}ardy-{W}einberg expectations within each form in the {DRC}. {N}either recent reproductive isolation alone nor selection alone can explain these results, a situation that is compatible with incipient speciation. {B}ecause it is possible that the molecular forms play different roles in malaria transmission, future studies should treat them separately.},
  keywords = {{PALUDISME} ; {VECTEUR} ; {MOUSTIQUE} ; {GENETIQUE} {DE} {POPULATION} ; {STRUCTURE} {GENETIQUE} ; {STRUCTURE} {DE} {POPULATION} ; {GENOTYPE} ; {DISTANCE} {GENETIQUE} ; {REPARTITION} {GEOGRAPHIQUE} ; {MARQUEUR} {MICROSATELLITE} ; {FLUX} {DE} {GENES} ; {AFRIQUE}},
  booktitle = {},
  journal = {{J}ournal of {H}eredity},
  volume = {94},
  numero = {2},
  pages = {133--147},
  ISSN = {0022-1503},
  year = {2003},
  DOI = {10.1093/jhered/esg024},
  URL = {https://www.documentation.ird.fr/hor/fdi:010050149},
}