@article{fdi:010049804, title = {{B}lood-feeding and immunogenic {A}edes aegypti saliva proteins}, author = {{W}asinpiyamongkol, {L}. and {P}atramool, {S}irilaksana and {L}uplertlop, {N}. and {S}urasombatpattana, {P}. and {D}oucoure, {S}ouleymane and {M}ouchet, {F}ran{\c{c}}ois and {S}{\'e}veno, {M}. and {R}emou{\'e}, {F}ranck and {D}emettre, {E}. and {B}rizard, {J}ean-{P}aul and {J}ouin, {P}. and {B}iron, {D}.{G}. and {T}homas, {F}. and {M}iss{\'e}, {D}oroth{\'e}e}, editor = {}, language = {{ENG}}, abstract = {{M}osquito-transmitted pathogens pass through the insect's midgut ({MG}) and salivary gland ({SG}). {W}hat occurs in these organs in response to a blood meal is poorly understood, but identifying the physiological differences between sugar-fed and blood-fed ({BF}) mosquitoes could shed light on factors important in pathogens transmission. {W}e compared differential protein expression in the {MG}s and {SG}s of female {A}edes aegypti mosquitoes after a sugar- or blood-based diet. {N}o difference was observed in the {MG} protein expression levels but certain {SG} proteins were highly expressed only in {BF} mosquitoes. {I}n sugar-fed mosquitoes, housekeeping proteins were highly expressed (especially those related to energy metabolism) and actin was up-regulated. {T}he immunofluorescence assay shows that there is no disruption of the {SG} cytoskeletal after the blood meal. {W}e have generated for the first time the 2-{DE} profiles of immunogenic {A}e. aegypti {SG} {BF}-related proteins. {T}hese new data could contribute to the understanding of the physiological processes that appear during the blood meal.}, keywords = {{DENGUE} ; {VECTEUR} ; {MOUSTIQUE} ; {VIRUS} ; {TRANSMISSION} ; {APPAREIL} {DIGESTIF} ; {REPAS} ; {SANG} ; {PHYSIOLOGIE} ; {METABOLISME} ; {PROTEINE} ; {IMMUNITE} ; {REPAS} {DE} {SANG} ; {PROTEOMIQUE} ; {EXPRESSION} {DES} {GENES} ; {GLANDE} {SALIVAIRE} ; {MONDE}}, booktitle = {}, journal = {{P}roteomics}, volume = {10}, numero = {10}, pages = {1906--1916}, ISSN = {1615-9861}, year = {2010}, DOI = {10.1002/pmic.200900626}, URL = {https://www.documentation.ird.fr/hor/fdi:010049804}, }