@article{fdi:010049620,
  title = {{H}uman antibody response to {A}nopheles gambiae saliva : an immuno-epidemiological biomarker to evaluate the efficacy of insecticide-treated nets in malaria vector control},
  author = {{D}ram{\'e}, {P}apa {M}aktar and {P}oinsignon, {A}nne and {B}esnard, {P}. and {L}e {M}ire, {J}. and {D}os-{S}antos, {M}. {A}. and {S}ow, {C}. {S}. and {C}orn{\'e}lie, {S}ylvie and {F}oumane, {V}. and {T}oto, {J}. {C}. and {S}emb{\`e}ne, {M}. and {B}oulanger, {D}enis and {S}imondon, {F}ran{\c{c}}ois and {F}ortes, {F}. and {C}arnevale, {P}ierre and {R}emou{\'e}, {F}ranck},
  editor = {},
  language = {{ENG}},
  abstract = {{F}or the fight against malaria, the {W}orld {H}ealth {O}rganization ({WHO}) has emphasized the need for indicators to evaluate the efficacy of vector-control strategies. {T}his study investigates a potential immunological marker, based on human antibody responses to {A}nopheles saliva, as a new indicator to evaluate the efficacy of insecticide-treated nets ({ITN}s). {P}arasitological, entomological, and immunological assessments were carried out in children and adults from a malaria-endemic region of {A}ngola before and after the introduction of {ITN}s. {I}mmunoglobulin {G} ({I}g{G}) levels to {A}n. gambiae saliva were positively associated with the intensity of {A}n. gambiae exposure and malaria infection. {A} significant decrease in the anti-saliva {I}g{G} response was observed after the introduction of {ITN}s, and this was associated with a drop in parasite load. {T}his study represents the first stage in the development of a new indicator to evaluate the efficacy of malaria vector-control strategies, which could apply in other arthropod vector-borne diseases.},
  keywords = {{ANGOLA}},
  booktitle = {},
  journal = {{A}merican {J}ournal of {T}ropical {M}edicine and {H}ygiene},
  volume = {83},
  numero = {1},
  pages = {115--121},
  ISSN = {0002-9637},
  year = {2010},
  DOI = {10.4269/ajtmh.2010.09-0684},
  URL = {https://www.documentation.ird.fr/hor/fdi:010049620},
}