%0 Journal Article
%9 ACL : Articles dans des revues avec comité de lecture répertoriées par l'AERES
%A Carvalho, A. G. C.
%A de Lira, P. I. C.
%A Barros, M. D. A.
%A Alessio, M. L. M.
%A Lima, M. D.
%A Carbonneau, M. A.
%A Berger, Jacques
%A Leger, C. L.
%T Diagnosis of iron deficiency anemia in children of Northeast Brazil = Diagnóstico de anemia por defi ciência de ferro em crianças do Nordeste do Brasil
%D 2010
%L fdi:010049597
%G ENG
%J Revista de Saude Publica
%@ 0034-8910
%K Anemia, Iron Deficiency, diagnosis ; Ferritins, blood ; Laboratory ; Techniques and Procedures ; Hematologic Tests ; Iron Deficiency, ; prevention and control ; Infant Nutrition ; Child Nutrition
%M ISI:000278873400015
%N 3
%P 513-519
%U https://www.documentation.ird.fr/hor/fdi:010049597
%> https://www.documentation.ird.fr/intranet/publi/2010/07-1/010049597.pdf
%V 44
%W Horizon (IRD)
%X OBJECTIVE: To diagnose iron deficiency anemia in children. METHODS: The study was conducted with a sample of 301 children aged six to 30 months attending public daycare centers in the city of Recife, Northeast Brazil, in 2004. The diagnoses of anemia were based on a combination of different hematological and biochemical parameters: hemoglobin, mean corpuscular volume, ferritin, C-reactive protein, transferrin saturation and transferrin receptor. The chi-square test and ANOVA were used in the statistical analysis. RESULTS: Of all children studied, 92.4% had anemia (Hb <110 g/L) and 28.9% had moderate/severe anemia (Hb <90 g/L). Lower levels of hemoglobin were found in children aged 6-17 months. Iron deficiency was found in 51.5% of children using ferritin (<12 mu g/L) as parameter. Taking into consideration the combination of hemoglobin level, ferritin and transferrin receptor, 58.1% had anemia with iron deficiency, 34.2% had anemia without iron deficiency and 2.3% had iron deficiency without anemia. Mean ferritin concentration was significantly higher in children with high C-reactive protein when compared with those with normal levels (22.1 vs. 14.8 mu g/L). CONCLUSIONS: The use of several biochemical and hematological parameters allowed to diagnosing iron deficiency anemia in two thirds of children, suggesting a need to identify other determinants of anemia without iron deficiency.
%$ 050 ; 054