@article{fdi:010049575, title = {{R}isk factors for {S}chistosoma haematobium infection and morbidity in two villages with different transmission patterns in {N}iger}, author = {{G}arba, {A}. and {P}ion, {S}{\'e}bastien and {C}ournil, {A}mandine and {M}ilet, {J}acqueline and {S}chneider, {D}ominique and {C}ampagne, {G}. and {C}hippaux, {J}ean-{P}hilippe and {B}oulanger, {D}enis}, editor = {}, language = {{ENG}}, abstract = {{A} better control of major neglected tropical diseases such as schistosomiasis is urgently needed to reduce their impact on public health in developing countries. {T}o optimize the efficiency of intervention campaigns, we assessed the influence of individual human factors on the level of {S}chistosoma haematobium infection and morbidity in a typical {S}ahelian country ({N}iger). {R}andom samples of 246 and 257 individuals were selected from general census in two villages with distinct patterns of schistosome transmission. {O}ne village ({L}ossa) is located in an area of perennial transmission whereas transmission is seasonal in the other village ({T}ara). {D}espite comparable levels of both egg excretion and lower tract pathology in the two villages, the inhabitants of {L}ossa had a higher risk ({OR}: 2.1, 95% {C}l: 1.1-3.9) of developing upper tract lesions compared to those living in {T}ara. {I}n both villages, bladder lesions were more serious in males than in females. {C}hildren between 7 and 15 years old were the most at risk to experience heavy infections ({OR}: 3.4,95% {CI}: 2.1-5.7), bladder ({OR}: 4.5,95% {C}l: 2.6-7.8) and upper tract ({OR}: 10.4,95% {C}l: 2.4-45.0) lesions, independently of gender and village. {T}hese results confirm that targeted intervention campaigns should include foci regardless of their schistosome transmission pattern and focus on the school-aged population.}, keywords = {{S}chistosoma haematobium ; {E}pidemiology ; {P}arasitology ; {M}orbidity ; {N}iger ; {T}ransmission pattern}, booktitle = {}, journal = {{A}cta {T}ropica}, volume = {115}, numero = {1-2}, pages = {84--89}, ISSN = {0001-706{X}}, year = {2010}, DOI = {10.1016/j.actatropica.2010.02.007}, URL = {https://www.documentation.ird.fr/hor/fdi:010049575}, }