@article{fdi:010049552,
  title = {{F}ield efficacy of a new mosaic long-lasting mosquito net ({P}erma{N}et ({R}) 3.0) against pyrethroid-resistant malaria vectors : a multi centre study in {W}estern and {C}entral {A}frica},
  author = {{C}orbel, {V}incent and {C}habi, {J}oseph and {D}abir{\'e}, {R}. {K}. and {E}tang, {J}. and {N}wane, {P}. and {P}igeon, {O}. and {A}kogbeto, {M}. and {H}ougard, {J}ean-{M}arc},
  editor = {},
  language = {{ENG}},
  abstract = {{B}ackground: {D}ue to the spread of pyrethroid-resistance in malaria vectors in {A}frica, new strategies and tools are urgently needed to better control malaria transmission. {T}he aim of this study was to evaluate the performances of a new mosaic long-lasting insecticidal net ({LLIN}), i.e. {P}erma{N}et ({R}) 3.0, against wild pyrethroid-resistant {A}nopheles gambiae s.l. in {W}est and {C}entral {A}frica. {M}ethods: {A} multi centre experimental hut trial was conducted in {M}alanville ({B}enin), {V}allee du {K}ou ({B}urkina {F}aso) and {P}itoa ({C}ameroon) to investigate the exophily, blood feeding inhibition and mortality induced by {P}erma{N}et ({R}) 3.0 (i.e. a mosaic net containing piperonyl butoxide and deltamethrin on the roof) comparatively to the {WHO} recommended {P}erma{N}et ({R}) 2.0 (unwashed and washed 20-times) and a conventionally deltamethrin-treated net ({CTN}). {R}esults: {T}he personal protection and insecticidal activity of {P}erma{N}et 3.0 and {P}erma{N}et ({R}) 2.0 were excellent (>80%) in the "pyrethroid-tolerant" area of {M}alanville. {I}n the pyrethroid-resistance areas of {P}itoa (metabolic resistance) and {V}allee du {K}ou (presence of the {L}1014{F} kdr mutation), {P}erma{N}et ({R}) 3.0 showed equal or better performances than {P}erma{N}et ({R}) 2.0. {I}t should be noted however that the deltamethrin content on {P}erma{N}et ({R}) 3.0 was up to twice higher than that of {P}erma{N}et ({R}) 2.0. {S}ignificant reduction of efficacy of both {LLIN} was noted after 20 washes although {P}erma{N}et ({R}) 3.0 still fulfilled the {WHO} requirement for {LLIN}. {C}onclusion: {T}he use of combination nets for malaria control offers promising prospects. {H}owever, further investigations are needed to demonstrate the benefits of using {P}erma{N}et ({R}) 3.0 for the control of pyrethroid resistant mosquito populations in {A}frica.},
  keywords = {},
  booktitle = {},
  journal = {{M}alaria {J}ournal},
  volume = {9},
  numero = {},
  pages = {113},
  ISSN = {1475-2875},
  year = {2010},
  DOI = {10.1186/1475-2875-9-113},
  URL = {https://www.documentation.ird.fr/hor/fdi:010049552},
}