@article{fdi:010049506,
  title = {{C}oxiella burnetii in humans and ticks in {R}ural {S}enegal},
  author = {{M}ediannikov, {O}leg and {F}enollar, {F}. and {S}ocolovschi, {C}. and {D}iatta, {G}. and {B}assene, {H}. and {M}olez, {J}ean-{F}ran{\c{c}}ois and {S}okhna, {C}heikh and {T}rape, {J}ean-{F}ran{\c{c}}ois and {R}aoult, {D}idier},
  editor = {},
  language = {{ENG}},
  abstract = {{B}ackground: {Q} fever is a worldwide zoonotic disease caused by {C}oxiella burnetii. {E}pidemiologically, animals are considered reservoirs and humans incidental hosts. {M}ethodology/{P}rincipal {F}indings: {W}e investigated {Q} fever in rural {S}enegal. {H}uman samples (e.g., sera, saliva, breast milk, feces) were screened in the generally healthy population of two villages of the {S}ine-{S}aloum region. {T}icks were collected in four regions. {S}eroprevalence was studied by immunofluorescence, and all other samples were tested by two q{PCR} systems for detection of {C}. burnetii. {P}ositive samples were genotyped (multispacer typing) by amplification and sequencing of three spacers. {S}trains were isolated by cell culture. {W}e found that the seroprevalence may be as high as 24.5% (59 of 238 studied) in {D}ielmo village. {W}e identified spontaneous excretion of {C}. burnetii by humans through faeces and milk. {H}ard and soft ticks (8 species) were infected in 0-37.6%. {W}e identified three genotypes of {C}. burnetii. {T}he previously identified genotype 6 was the most common in ticks in all studied regions and the only one found in human samples. {T}hree strains of genotype 6 of {C}. burnetii were also recovered from soft tick {O}rnithodoros sonrai. {T}wo other genotypes found in ticks, 35 and 36, were identified for the first time. {C}onclusions/{S}ignificance: {Q} fever should be considered a significant public health threat in {S}enegal. {H}umans, similar to other mammals, may continuously excrete {C}. burnetii.},
  keywords = {{SENEGAL}},
  booktitle = {},
  journal = {{P}los {N}eglected {T}ropical {D}iseases},
  volume = {4},
  numero = {4},
  pages = {e654},
  ISSN = {1935-2727},
  year = {2010},
  DOI = {10.1371/journal.pntd.0000654},
  URL = {https://www.documentation.ird.fr/hor/fdi:010049506},
}