@article{fdi:010049477, title = {{C}omparative sequence analyses indicate that {C}offea ({A}sterids) and {V}itis ({R}osids) derive from the same paleo-hexaploid ancestral genome}, author = {{C}enci, {A}lberto and {C}ombes, {M}arie-{C}hristine and {L}ashermes, {P}hilippe}, editor = {}, language = {{ENG}}, abstract = {{T}he complete sequence of {V}itis vinifera revealed that the rosid clade derives from a hexaploid ancestor. {A}t present, no analysis of complete genome sequence is available for an asterid, the other large eudicot clade, which includes the economically important species potato, tomato and coffee. {T}o elucidate the genomic history of asterids, we compared the sequence of an 800 kb region of diploid {C}offea genome to the orthologous regions of {V}. vinifera, {P}opulus trichocarpa and {A}rabidopsis thaliana. {W}e found a very high level of collinearity between around 80 genes of the three rosid species and {C}offea. {C}ollinearity comparisons between orthologous and paralogous regions indicates that (1) the {C}offea (and consequently all asterids) and rosids share the same hexaploid ancestor; (2) the diploidization process (loss of duplicated and redundant copies from the whole genome duplication) was very advanced in the most recent common ancestor of rosids and asterids. {F}inally, no additional polyploidization events were detected in the {C}offea lineage. {D}ifferences in gene loss rates were detected among the three rosid species and linked to the divergence in protein sequences.}, keywords = {{P}aleo-polyploid ; {C}omparative genomics ; {C}offea ; {A}sterids ; {R}osids}, booktitle = {}, journal = {{M}olecular {G}enetics and {G}enomics}, volume = {283}, numero = {5}, pages = {493--501}, ISSN = {1617-4615}, year = {2010}, DOI = {10.1007/s00438-010-0534-7}, URL = {https://www.documentation.ird.fr/hor/fdi:010049477}, }