@article{fdi:010049366,
  title = {{L}a trypanosomose humaine africaine en faci{\`e}s {\'e}pid{\'e}miologique de mangrove. {P}r{\'e}sentation, d{\'e}terminants et prise en charge dans le contexte de la {G}uin{\'e}e (2005 {\`a} 2007) = {H}uman {A}frican {T}rypanosomiasis in mangrove epidemiologic area. {P}resentation, diagnosis and treatment in {G}uinea, 2005-2007},
  author = {{V}anhecke, {C}. and {G}uevart, {E}. and {E}zzedine, {K}. and {R}eceveur, {M}. {C}. and {J}amonneau, {V}incent and {B}ucheton, {B}runo and {C}amara, {M}. and {V}incendeau, {P}. and {M}alvy, {D}.},
  editor = {},
  language = {{FRE}},
  abstract = {{G}ambiense human {A}frican trypanosomiasis is still assumed to be endemic in many part of {W}est {A}frica, particularly in {G}uinea coastal area with mangrove swamp. {D}iagnosis is usually made during active medical screening or by passive initiative. {O}bjectives. - {T}o describe clinical and epidemiological characteristics of {G}ambiense human {A}frican trypanosomiasis in the coastal area of {G}uinea. {M}ethods. - {E}xhaustive and retrospective analysis of all patients attending the trypanosomiasis center in the coastal area of {G}uinea between {J}anuary 2005 and {D}ecember 2007 with a diagnosis of human {A}frican trypanosomiasis. {R}esults. - {A} total of 196 patients were recruited for the study. out of them, 55 % of the 73 patients diagnosed during active screening were classified stage {I} (haemolymphatic stage) or early stage 2 (meningoencephalitic stage). {C}ontrarily, 115 of the 120 diagnosed by passive procedure were classified late stage 2, which features more specific signs and neurological symptoms, and leads to coma and death. {M}ore than 90 % of all cases presented cervical lymph nodes with identification of trypanosome on direct examination of fluid puncture. {L}ess than one third of the patients were reexamined three months later. {D}iscussion. - {I}n the coastal area of {G}uinea with mangrove swamp, direct examination of lymph node fluid puncture seems to be the most contributive test for the diagnosis of human {A}frican trypanosomiasis. {H}ence, associating clinical examination of cervical lymph nodes area and direct examination of fluid puncture may allow an early diagnosis of {G}ambiense human {A}frican trypanosomiasis and favor the implementation of efficient therapeutic strategies.},
  keywords = {{C}ervical lymph nodes ; {G}uinea ; {M}angrove swamp ; {G}ambiense human {A}frican ; trypanosomiasis},
  booktitle = {},
  journal = {{P}athologie {B}iologie},
  volume = {58},
  numero = {1},
  pages = {110--116},
  ISSN = {0369-8114},
  year = {2010},
  DOI = {10.1016/j.patbio.2009.07.033},
  URL = {https://www.documentation.ird.fr/hor/fdi:010049366},
}