@article{fdi:010049212,
  title = {{M}olecular epidemiology of {S}imian immunodeficiency virus infection in wild-living gorillas},
  author = {{N}eel, {C}{\'e}cile and {E}tienne, {L}ucie and {L}i, {Y}.{Y}. and {T}akehisa, {J}. and {R}udicell, {R}.{S}. and {B}ass, {I}.{N}. and {M}oudindo, {J}. and {M}ebenga, {A}. and {E}steban, {A}mandine and {V}an {H}euverswyn, {F}. and {L}i{\'e}geois, {F}lorian and {K}ranzusch, {P}.{J}. and {W}alsh, {P}.{D}. and {S}anz, {C}.{M}. and {M}organ, {D}.{B}. and {N}django, {J}.{B}.{N}. and {P}lantier, {J}.{C}. and {L}ocatelli, {S}abrina and {G}onder, {M}.{K}. and {L}eendertz, {F}.{H}. and {B}oesch, {C}. and {T}odd, {A}. and {D}elaporte, {E}ric and {M}poudi-{N}gole, {E}. and {H}ahn, {B}.{H}. and {P}eeters, {M}artine},
  editor = {},
  language = {{ENG}},
  abstract = {{C}himpanzees and gorillas are the only nonhuman primates known to harbor viruses closely related to {HIV}-1. {P}hylogenetic analyses showed that gorillas acquired the simian immunodeficiency virus {SIV}gor from chimpanzees, and viruses from the {SIV}cpz/{SIV}gor lineage have been transmitted to humans on at least four occasions, leading to {HIV}-1 groups {M}, {N}, {O}, and {P}. {T}o determine the geographic distribution, prevalence, and species association of {SIV}gor, we conducted a comprehensive molecular epidemiological survey of wild gorillas in {C}entral {A}frica. {G}orilla fecal samples were collected in the range of western lowland gorillas (n = 2,367) and eastern {G}rauer gorillas (n = 183) and tested for {SIV}gor antibodies and nucleic acids. {SIV}gor antibody-positive samples were identified at 2 sites in {C}ameroon, with no evidence of infection at 19 other sites, including 3 in the range of the {E}astern gorillas. {I}n {C}ameroon, based on {DNA} and microsatellite analyses of a subset of samples, we estimated the prevalence of {SIV}gor to be 1.6% (range, 0% to 4.6%), which is significantly lower than the prevalence of {SIV}cpz{P}tt in chimpanzees (5.9%; range, 0% to 32%). {A}ll newly identified {SIV}gor strains formed a monophyletic lineage within the {SIV}cpz radiation, closely related to {HIV}-1 groups {O} and {P}, and clustered according to their field site of origin. {A}t one site, there was evidence for intergroup transmission and a high intragroup prevalence. {T}hese isolated hot spots of {SIV}gor-infected gorilla communities could serve as a source for human infection. {T}he overall low prevalence and sporadic distribution of {SIV}gor could suggest a decline of {SIV}gor in wild populations, but it cannot be excluded that {SIV}gor is still more prevalent in other parts of the geographical range of gorillas.},
  keywords = {{CAMEROUN} ; {AFRIQUE} {CENTRALE}},
  booktitle = {},
  journal = {{J}ournal of {V}irology},
  volume = {84},
  numero = {3},
  pages = {1464--1476},
  ISSN = {0022-538{X}},
  year = {2010},
  DOI = {10.1128/jvi.02129-09},
  URL = {https://www.documentation.ird.fr/hor/fdi:010049212},
}