@article{fdi:010049197,
  title = {{I}nsecticide resistance in {A}nopheles gambiae : data from the first year of a multi-country study highlight the extent of the problem},
  author = {{R}anson, {H}. and {A}bdallah, {H}. and {B}adolo, {A}. and {G}uelbeogo, {W}. {M}. and {K}erah-{H}inzoumbe, {C}. and {Y}angalbe-{K}alnone, {E}. and {S}agnon, {N}. and {S}imard, {F}r{\'e}d{\'e}ric and {C}oetzee, {M}.},
  editor = {},
  language = {{ENG}},
  abstract = {{B}ackground: {I}nsecticide resistance in malaria vectors is a growing concern in many countries which requires immediate attention because of the limited chemical arsenal available for vector control. {T}he current extent and distribution of this resistance in many parts of the continent is unknown and yet such information is essential for the planning of effective malaria control interventions. {M}ethods: {I}n 2008, a network was established, with financial support from {WHO}/{TDR}, to investigate the extent of insecticide resistance in malaria vectors in five {A}frican countries. {H}ere, the results of bioassays on {A}nopheles gambiae sensu lato from two rounds of monitoring from 12 sentinel sites in three of the partner countries are reported. {R}esults: {R}esistance is very heterogeneous even over relatively small distances. {F}urthermore, in some sites, large differences in mortality rates were observed during the course of the malaria transmission season. {U}sing {WHO} diagnostic doses, all populations from {B}urkina {F}aso and {C}had and two of the four populations from {S}udan were classified as resistant to permethrin and/or deltamethrin. {V}ery high frequencies of {DDT} resistance were found in urban areas in {B}urkina {F}aso and {S}udan and in a cotton-growing district in {C}had. {I}n areas where both {A}n. gambiae s.s. and {A}nopheles arabiensis were present, resistance was found in both species, although generally at a higher frequency in {A}n gambiae s.s. {A}nopheles gambiae s.l. remains largely susceptible to the organophosphate fenitrothion and the carbamate bendiocarb in the majority of the sentinel sites with the exception of two sites in {B}urkina {F}aso. {I}n the cotton-growing region of {S}oumousso in {B}urkina {F}aso, the vector population is resistant to all four classes of insecticide available for malaria control. {C}onclusions: {P}ossible factors influencing the frequency of resistant individuals observed in the sentinel sites are discussed. {T}he results of this study highlight the importance of standardized longitudinal insecticide resistance monitoring and the urgent need for studies to monitor the impact of this resistance on malaria vector control activities.},
  keywords = {},
  booktitle = {},
  journal = {{M}alaria {J}ournal},
  volume = {8},
  numero = {},
  pages = {299},
  ISSN = {1475-2875},
  year = {2009},
  DOI = {10.1186/1475-2875-8-299},
  URL = {https://www.documentation.ird.fr/hor/fdi:010049197},
}