@article{fdi:010049089,
  title = {{G}enetic diversity among human immunodeficiency virus-1 non-{B} subtypes in viral load and drug resistance assays},
  author = {{P}eeters, {M}artine and {A}ghokeng {F}obang, {A}velin and {D}elaporte, {E}ric},
  editor = {},
  language = {{ENG}},
  abstract = {{T}he tremendous diversity of human immunodeficiency virus ({HIV})-1 strains circulating worldwide has an important impact on almost all aspects of the management of this infection, from the identification of infected persons, through treatment efficacy and monitoring, and prevention strategies such as vaccine design. {T}he areas where {HIV}-1 genetic diversity is highest are those where the majority of patients in need of treatment and biological monitoring live. {W}ith increased access to treatment in these areas, it is expected that the demand for monitoring tools such as viral load assays and resistance tests will also increase, and their reliability will be critical. {R}egular updates of these assays during the last two decades have aimed at improving their performances in different ways that include their reliability with different {HIV}-1 strains. {W}e here review to what extent {HIV}-1 genetic diversity still limits or not the use of currently available viral load and resistance tests.},
  keywords = {{D}rug resistance test ; genetic diversity ; {HIV}-1 ; review ; viral load},
  booktitle = {},
  journal = {{C}linical {M}icrobiology and {I}nfection},
  volume = {16},
  numero = {10},
  pages = {1525--1531},
  ISSN = {1198-743{X}},
  year = {2010},
  DOI = {10.1111/j.1469-0691.2010.03300.x},
  URL = {https://www.documentation.ird.fr/hor/fdi:010049089},
}