@article{fdi:010048511, title = {{S}tructural studies of the {S}putnik virophage}, author = {{S}un, {S}. {Y}. and {L}a {S}cola, {B}. and {B}owman, {V}. {D}. and {R}yan, {C}. {M}. and {W}hitelegge, {J}. {P}. and {R}aoult, {D}idier and {R}ossmann, {M}. {G}.}, editor = {}, language = {{ENG}}, abstract = {{T}he virophage {S}putnik is a satellite virus of the giant mimivirus and is the only satellite virus reported to date whose propagation adversely affects its host virus' production. {G}enome sequence analysis showed that {S}putnik has genes related to viruses infecting all three domains of life. {H}ere, we report structural studies of {S}putnik, which show that it is about 740 angstrom in diameter, has a {T} = 27 icosahedral capsid, and has a lipid membrane inside the protein shell. {S}tructural analyses suggest that the major capsid protein of {S}putnik is likely to have a double jelly-roll fold, although sequence alignments do not show any detectable similarity with other viral double jelly-roll capsid proteins. {H}ence, the origin of {S}putnik's capsid might have been derived from other viruses prior to its association with mimivirus.}, keywords = {}, booktitle = {}, journal = {{J}ournal of {V}irology}, volume = {84}, numero = {2}, pages = {894--897}, ISSN = {0022-538{X}}, year = {2010}, DOI = {10.1128/jvi.01957-09}, URL = {https://www.documentation.ird.fr/hor/fdi:010048511}, }