@article{fdi:010048503,
  title = {{S}ynergy between repellents and organophosphates on bed nets: efficacy and behavioural response of natural free-flying {A}n. gambiae mosquitoes},
  author = {{P}ennetier, {C}{\'e}dric and {C}ostantini, {C}arlo and {C}orbel, {V}incent and {L}icciardi, {S}{\`e}verine and {D}abir{\'e}, {R}. {K}. and {L}apied, {B}. and {C}handre, {F}abrice and {H}ougard, {J}ean-{M}arc},
  editor = {},
  language = {{ENG}},
  abstract = {{B}ackground: {C}hemicals are used on bed nets in order to prevent infected bites and to kill aggressive malaria vectors. {B}ecause pyrethroid resistance has become widespread in the main malaria vectors, research for alternative active ingredients becomes urgent. {M}ixing a repellent and a non-pyrethroid insecticide seemed to be a promising tool as mixtures in the laboratory showed the same features as pyrethroids. {M}ethodology/{P}rincipal {F}indings: {W}e present here the results of two trials run against free-flying {A}nopheles gambiae populations comparing the effects of two insect repellents (either {DEET} or {KBR} 3023, also known as icaridin) and an organophosphate insecticide at low-doses (pirimiphos-methyl, {PM}) used alone and in combination on bed nets. {W}e showed that mixtures of {PM} and the repellents induced higher exophily, blood feeding inhibition and mortality among wild susceptible and resistant malaria vectors than compounds used alone. {N}evertheless the synergistic interactions are only involved in the high mortality induced by the two mixtures. {C}onclusion: {T}hese field trials argue in favour of the strategy of mixing repellent and organophosphate on bed nets to better control resistant malaria vectors.},
  keywords = {},
  booktitle = {},
  journal = {{P}los {O}ne},
  volume = {4},
  numero = {11},
  pages = {e7896 [8 ]},
  ISSN = {1932-6203},
  year = {2009},
  DOI = {10.1371/journal.pone.0007896},
  URL = {https://www.documentation.ird.fr/hor/fdi:010048503},
}