@article{fdi:010048464,
  title = {{L}ow prevalence of {HIV} {T}ype 1 drug resistance mutations in untreated, recently infected patients from {B}urkina {F}aso, {C}ote d'{I}voire, {S}enegal, {T}hailand, and {V}ietnam : the {ANRS} 12134 study},
  author = {{A}youba, {A}hidjo and {L}ien, {T}.{T}.{X}. and {N}ouhin, {J}. and {V}ergne, {L}aurence and {A}ghokeng {F}obang, {A}velin and {N}go-{G}iang-{H}uong, {N}icole and {D}iop, {H}. and {T}our{\'e} {K}ane, {C}. and {V}al{\'e}a, {D}. and {R}ouet, {F}. and {J}oulia-{E}kaza, {D}. and {T}oni, {T}. d'{A}. and {N}errienet, {E}. and {M}poudi {N}gole, {E}. and {D}elaporte, {E}ric and {C}ostagliola, {D}. and {P}eeters, {M}artine and {C}haix, {M}.{L}.},
  editor = {},
  language = {{ENG}},
  abstract = {{T}he frequency of transmitted {HIV} drug resistance ({HIVDR}) was evaluated in the context of rapid scale-up of antiretroviral treatment in {T}hailand, {V}ietnam, {B}urkina {F}aso, {C}ote d'{I}voire, and {S}enegal by using an adaptation of the {WHO} generic protocol of the {HIV} {D}rug {R}esistance {T}hreshold {S}urvey ({HIVDR}-{TS}) for sample collection and classification. {R}esistance-associated mutations were interpreted using the 2009 {WHO} list for epidemiological surveys. {W}e included 266 subjects from the five study sites. {O}f the 266 {RT} and {PR} sequences analyzed, two from {V}ietnam harbored virus with major drug resistance mutations ({G}190{A} in {RT} for one individual and {M}46{I} in {PR} for the second individual). {P}hylogenetic analysis revealed that {CRF}01_{AE} predominates (>90%) in {T}hailand and {V}ietnam. {CRF}02 (>65%) cocirculates with other {HIV}-1 variants in {S}enegal and {C}ote d'{I}voire. {T}he prevalence of {HIVDRM} is scored as low (<= 5%) in all the five sites for the three drug classes analyzed. {A} continuous population survey for {HIVDRM} will provide a rational basis for maintaining or changing the current first line regimen in these countries.},
  keywords = {{BURKINA} {FASO} ; {COTE} {D}'{IVOIRE} ; {SENEGAL} ; {THAILANDE} ; {VIET} {NAM}},
  booktitle = {},
  journal = {{A}ids {R}esearch and {H}uman {R}etroviruses},
  volume = {25},
  numero = {11},
  pages = {1193--1196},
  ISSN = {0889-2229},
  year = {2009},
  DOI = {10.1089/aid.2009.0142},
  URL = {https://www.documentation.ird.fr/hor/fdi:010048464},
}