@article{fdi:010048445,
  title = {{CRF}45_{AKU}, a circulating recombinant from {C}entral {A}frica, is probably the common ancestor of {HIV} type 1 {MAL} and {HIV} type 1 {NOGIL}},
  author = {{N}iama, {F}.{R}. and {V}idal, {N}icole and {B}azepeo, {S}.{E}. and {M}poudi, {E}. and {T}oure-{K}ane, {C}. and {P}arra, {H}.{J}. and {D}elaporte, {E}ric and {P}eeters, {M}artine},
  editor = {},
  language = {{ENG}},
  abstract = {{I}n this study, we characterized four {HIV}-1 strains from {C}ameroon, {G}abon, and the {D}emocratic {R}epublic of {C}ongo ({DRC}), collected during independent serosurveys, and previously found to cluster in the pol gene with {HIV}-1{MAL} and {HIV}-1 {NOGIL}3, two complex recombinant viruses reported in the early {HIV} epidemic, and with the recombinant strain 04{FR}. {AUK} recently described in {F}rance. {T}he four newly sequenced viruses shared the same structure as 04{FR}. {AUK}, involving alternating fragments of subtype {A}, {K}, and unclassified ({U}) fragments, representing a new {CRF} called {CRF}45_{AKU}. {S}ome of the unclassified fragments were related to unclassified regions described in either {CRF}04 or {CRF}09 strains. {C}areful reanalysis of {HIV}-1 {MAL} and {HIV}-1 {NOGIL}3 demonstrated that these strains were related exclusively to {CRF}45_{AKU} and either two subtype {D} fragments for {HIV}-1 {MAL} or one subtype {H} segment for {HIV}-1 {NOGIL}3. {F}ollowing extensive blast searches, related gag, pol, and env sequences were observed in {C}entral and {W}est {A}frica ({S}enegal, {M}ali), as well as in {E}urope ({F}rance, {S}pain, {I}taly, {C}yprus), {A}rgentina, and {C}hina.},
  keywords = {{CAMEROUN} ; {GABON} ; {REPUBLIQUE} {DEMOCRATIQUE} {DU} {CONGO}},
  booktitle = {},
  journal = {{A}ids {R}esearch and {H}uman {R}etroviruses},
  volume = {25},
  numero = {12},
  pages = {1345--1353},
  ISSN = {0889-2229},
  year = {2009},
  DOI = {10.1089/aid.2009.0169},
  URL = {https://www.documentation.ird.fr/hor/fdi:010048445},
}