@article{fdi:010048435, title = {{M}anaging insecticide resistance in malaria vectors by combining carbamate-treated plastic wall sheeting and pyrethroid-treated bed nets}, author = {{D}j{\`e}nontin, {A}rmel and {C}habi, {J}oseph and {B}aldet, {T}hierry and {I}rish, {S}. and {P}ennetier, {C}{\'e}dric and {H}ougard, {J}ean-{M}arc and {C}orbel, {V}incent and {A}kogbeto, {M}. and {C}handre, {F}abrice}, editor = {}, language = {{ENG}}, abstract = {{B}ackground: {P}yrethroid resistance is now widespread in {A}nopheles gambiae, the major vector for malaria in sub-{S}aharan {A}frica. {T}his resistance may compromise malaria vector control strategies that are currently in use in endemic areas. {I}n this context, a new tool for management of resistant mosquitoes based on the combination of a pyrethroid-treated bed net and carbamate-treated plastic sheeting was developed. {M}ethods: {I}n the laboratory, the insecticidal activity and wash resistance of four carbamate-treated materials: a cotton/polyester blend, a polyvinyl chloride tarpaulin, a cotton/polyester blend covered on one side with polyurethane, and a mesh of polypropylene fibres was tested. {T}hese materials were treated with bendiocarb at 100 mg/m(2) and 200 mg/m(2) with and without a binding resin to find the best combination for field studies. {S}econdly, experimental hut trials were performed in southern {B}enin to test the efficacy of the combined use of a pyrethroid-treated bed net and the carbamate-treated material that was the most wash-resistant against wild populations of pyrethroid-resistant {A}n. gambiae and {C}ulex quinquefasciatus. {R}esults: {M}aterial made of polypropylene mesh ({PPW}) provided the best wash resistance (up to 10 washes), regardless of the insecticide dose, the type of washing, or the presence or absence of the binding resin. {T}he experimental hut trial showed that the combination of carbamate-treated {PPW} and a pyrethroid-treated bed net was extremely effective in terms of mortality and inhibition of blood feeding of pyrethroid-resistant {A}n. gambiae. {T}his efficacy was found to be proportional to the total surface of the walls. {T}his combination showed a moderate effect against wild populations of {C}x. quinquefasciatus, which were strongly resistant to pyrethroid. {C}onclusion: {T}hese preliminary results should be confirmed, including evaluation of entomological, parasitological, and clinical parameters. {S}elective pressure on resistance mechanisms within the vector population, effects on other pest insects, and the acceptability of this management strategy in the community also need to be evaluated.}, keywords = {{AFRIQUE} {SUBSAHARIENNE}}, booktitle = {}, journal = {{M}alaria {J}ournal}, volume = {8}, numero = {}, pages = {233 [9 ]}, ISSN = {1475-2875}, year = {2009}, DOI = {10.1186/1475-2875-8-233}, URL = {https://www.documentation.ird.fr/hor/fdi:010048435}, }