@article{fdi:010048322,
  title = {{S}patial distribution and risk factors of dengue and {J}apanese encephalitis virus infection in urban settings : the case of {V}ientiane, {L}ao {PDR}},
  author = {{V}all{\'e}e, {J}ulie and {D}ubot {P}{\'e}r{\`e}s, {A}udrey and {O}unaphom, {P}. and {S}ayavong, {C}. and {B}ryant, {J}.{E}. and {G}onzalez, {J}ean-{P}aul},
  editor = {},
  language = {{ENG}},
  abstract = {{OBJECTIVES} {T}o evaluate the prevalence of flavivirus infection in {V}ientiane city ({L}ao {PDR}), to describe the spatial distribution of infection within this city, and to explore the link between flavivirus seroprevalence and urbanization levels of residential neighbourhoods. {METHODS} {A} seroprevalence survey was carried out in 2006 including 1990 adults (35 years) and 1568 children (>= 6months and < 6 years) randomly selected. {RESULTS} {T}he prevalence of individuals with previous flavivirus infection (i.e. negative for both {DEN} and {JE} {I}g{M} but positive for {DEN} {I}g{G}) was 57.7%, with a significantly ({P} < 0.001) higher prevalence among adults (84.6%; 95% confidence interval ({CI}) = 82.4-86.8) than children (9.4%; 95% {CI} = 7.2-11.6). {T}he prevalence of individuals with recent flavivirus infection (i.e. positive for {DEN} and/or {JE} {I}g{M}) was 6.5% and also significantly ({P} < 0.001) higher among adults (10.0%; 95% {CI} = 8.3-11.7) than children (2.5%; 95% {CI} = 1.5-3.5). {I}n terms of spatial distribution, {I}g{G} prevalence was significantly ({P} < 0.001) higher among individuals living in the central city (60.1%; 95% {CI} = 56.2-64.1) than among those living in the periphery (44.3%; 95% {CI} = 41.5-47.2). {I}n contrast, seroprevalence of recent flavivirus infections was significantly ({P} < 0.001) higher among individuals living in the periphery (8.8%; 95% {CI} = 6.9-10.7) than in the central city (4.0%; 95% {CI} = 2.9-5.2). {T}his association was also statistically consistant ({P} < 0.01) in multivariate logistic regression after controlling for individual risk factors. {CONCLUSIONS} {O}ur findings indicate that the level of urbanization of residential neighbourhoods influences the risk of flavivirus infection. {T}he spatial distribution of flavivirus infection varies, even within a small city of less than 300 000 habitants such as {V}ientiane.},
  keywords = {{V}ientiane ; spatial distribution ; urbanization ; residential neighbourhood ; serosurvey ; {D}engue and {J}apanese encephalitis ; {LAOS}},
  booktitle = {},
  journal = {{T}ropical {M}edicine and {I}nternational {H}ealth},
  volume = {14},
  numero = {9},
  pages = {1134--1142},
  ISSN = {1360-2276},
  year = {2009},
  DOI = {10.1111/j.1365-3156.2009.02319.x},
  URL = {https://www.documentation.ird.fr/hor/fdi:010048322},
}