@article{fdi:010048220,
  title = {{S}urprisingly high prevalence of subtype {C} and specific {HIV}-1 subtype/{CRF} distribution in men having sex with men in {S}enegal},
  author = {{N}diaye, {H}. {D}. and {T}oure-{K}ane, {C}. and {V}idal, {N}icole and {N}iama, {F}. {R}. and {N}iang-{D}iallo, {P}. {A}. and {D}ieye, {T}. and {G}ave-{D}iallo, {A}. and {W}ade, {A}. {S}. and {P}eeters, {M}artine and {M}boup, {S}.},
  editor = {},
  language = {{ENG}},
  abstract = {{B}ackground: {R}ecent reports showed the high vulnerability for {HIV} infection of men who have sex with men ({MSM}) in {A}frica. {H}ere, we report the {HIV}-1 variants that circulate among {MSM} in {S}enegal. {M}ethods: {HIV}-1 subtype/circulating recombinant form ({CRF}) was determined in an 1800-base pair fragment of pol for 70 {HIV}-1-positive samples from {MSM}. {P}hylogenetic trees were constructed using the neighbor-joining method with {CLUSTALX}. {S}imilarity and bootstrap plots were then done for recombination analysis. {T}he maximum likelihood approach was used for the identification of transmission clusters. {R}esults: {S}ixty-seven samples (95%) were from {S}enegalese {MSM}, 90% unmarried with a median age of 30 years. {F}ifty-five {MSM} had regular male partners, but 39 of 70 had also a regular female partner. {T}he overall subtype/{CRF} distribution was as follows: 28 {C} (40%), 17 {CRF}02_{AG} (24.3%), 13 {B} (18.6%), 6 {G} (8.6%), 3 {CRF}09_cpx (4.3%), and 3 (4.3%) unique recombinants. {I}n addition, 47 sequences (67.15%) were segregated into 15 transmission clusters. {C}onclusions: {T}hese variants circulate also among the general population or female sex workers, but the proportions are significantly different. {D}espite the massive stigma, the majority (80%) of {MSM} recognized having sex with women and could serve as a bridge for intermixing of {HIV}-1 variants between high-risk men and low-risk women.},
  keywords = {{HIV}-1 diversity ; {MSM} ; {S}enegal ; subtype {C}},
  booktitle = {},
  journal = {{J}aids - {J}ournal of {A}cquired {I}mmune {D}eficiency {S}yndromes},
  volume = {52},
  numero = {2},
  pages = {249--252},
  ISSN = {1525-4135},
  year = {2009},
  URL = {https://www.documentation.ird.fr/hor/fdi:010048220},
}